4.8 Review

A perspective on HPK1 as a novel immuno-oncology drug target

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer

Xianzhou Song et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Multidisciplinary Sciences

VISTA is a checkpoint regulator for naive T cell quiescence and peripheral tolerance

Mohamed A. ElTanbouly et al.

SCIENCE (2020)

Review Cell Biology

Cyclooxygenase-2 in cancer: A review

Nasser Hashemi Goradel et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Article Biochemistry & Molecular Biology

Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer

Ping Wu et al.

STRUCTURE (2019)

Editorial Material Biochemistry & Molecular Biology

The Structure of HPK1 Kinase Domain: To Boldly Go Where No Immuno-Oncology Drugs Have Gone Before

Sansana Sawasdikosol et al.

STRUCTURE (2019)

Article Immunology

Defining 'T cell exhaustion'

Christian U. Blank et al.

NATURE REVIEWS IMMUNOLOGY (2019)

Review Oncology

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy

Jonathan J. Havel et al.

NATURE REVIEWS CANCER (2019)

Review Multidisciplinary Sciences

Cancer immunotherapy using checkpoint blockade

Antoni Ribas et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

Vishal Khairnar et al.

NATURE COMMUNICATIONS (2018)

Review Oncology

Treg Fragility: A Prerequisite for Effective Antitumor Immunity?

Abigail E. Overacre-Delgoffe et al.

CANCER IMMUNOLOGY RESEARCH (2018)

Review Immunology

Regulatory mechanisms in T cell receptor signalling

Guillaume Gaud et al.

NATURE REVIEWS IMMUNOLOGY (2018)

Review Immunology

Tim-3 and its role in regulating anti-tumor immunity

Madhumita Das et al.

IMMUNOLOGICAL REVIEWS (2017)

Review Immunology

TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy

William C. Dougall et al.

IMMUNOLOGICAL REVIEWS (2017)

Review Multidisciplinary Sciences

Elements of cancer immunity and the cancer-immune set point

Daniel S. Chen et al.

NATURE (2017)

Review Immunology

TIGIT: A Key Inhibitor of the Cancer Immunity Cycle

Nicholas A. Manieri et al.

TRENDS IN IMMUNOLOGY (2017)

Review Oncology

CEACAM1 as a multi-purpose target for cancer immunotherapy

Matthew Dankner et al.

ONCOIMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity

Abigail E. Overacre-Delgoffe et al.

Review Oncology

The immunobiology of myeloid-derived suppressor cells in cancer

Morteza Motallebnezhad et al.

TUMOR BIOLOGY (2016)

Review Chemistry, Medicinal

Cancer Immunotherapy: Selected Targets and Small-Molecule Modulators

Hilmar Weinmann

CHEMMEDCHEM (2016)

Article Pharmacology & Pharmacy

Immunosuppressive activities of adenosine in cancer

Bertrand Allard et al.

CURRENT OPINION IN PHARMACOLOGY (2016)

Article Biotechnology & Applied Microbiology

Big opportunities for small molecules in immuno-oncology

Jerry L. Adams et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

Review Oncology

Immune evasion in cancer: Mechanistic basis and therapeutic strategies

Dass S. Vinay et al.

SEMINARS IN CANCER BIOLOGY (2015)

Review Immunology

Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators

Isabelle Le Mercier et al.

FRONTIERS IN IMMUNOLOGY (2015)

Review Oncology

Trafficking of T Cells into Tumors

Clare Y. Slaney et al.

CANCER RESEARCH (2014)

Review Immunology

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

Eric O. Long et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Review Immunology

Oncology Meets Immunology: The Cancer-Immunity Cycle

Daniel S. Chen et al.

IMMUNITY (2013)

Article Allergy

Natural killer cell biology: An update and future directions

Kerry S. Campbell et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Review Oncology

T-Regulatory Cells: Key Players in Tumor Immune Escape and Angiogenesis

Andrea Facciabene et al.

CANCER RESEARCH (2012)

Article Immunology

HPK1 as a novel target for cancer immunotherapy

Sansana Sawasdikosol et al.

IMMUNOLOGIC RESEARCH (2012)

Article Biochemistry & Molecular Biology

Attenuation of T Cell Receptor Signaling by Serine Phosphorylation-mediated Lysine 30 Ubiquitination of SLP-76 Protein

Xiaohong Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biotechnology & Applied Microbiology

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

Theonie Anastassiadis et al.

NATURE BIOTECHNOLOGY (2011)

Article Biotechnology & Applied Microbiology

Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis et al.

NATURE BIOTECHNOLOGY (2011)

Review Immunology

T cell exhaustion

E. John Wherry

NATURE IMMUNOLOGY (2011)

Article Immunology

HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion

Irene M. Patzak et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2010)

Article Oncology

Regulatory T cells in tumor immunity

Hiroyoshi Nishikawa et al.

INTERNATIONAL JOURNAL OF CANCER (2010)

Article Multidisciplinary Sciences

HPK1 Associates with SKAP-HOM to Negatively Regulate Rap1-Mediated B-Lymphocyte Adhesion

Sebastian Koenigsberger et al.

PLOS ONE (2010)

Review Immunology

T Cell Activation

Jennifer E. Smith-Garvin et al.

ANNUAL REVIEW OF IMMUNOLOGY (2009)

Article Biochemistry & Molecular Biology

The Adapter Protein SLP-76 Mediates Outside-In Integrin Signaling and Function in T Cells

R. G. Baker et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Immunology

Death receptor signal transducers: nodes of coordination in immune signaling networks

Nicholas S. Wilson et al.

NATURE IMMUNOLOGY (2009)

Article Multidisciplinary Sciences

Phosphorylation of CARMA1 by HPK1 is critical for NF-κB activation in T cells

Dirk Brenner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Oncology

Pro-inflammatory prostaglandins and progression of colorectal cancer

Dingzhi Wang et al.

CANCER LETTERS (2008)

Review Oncology

Concepts of activated T cell death

Dirk Brenner et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2008)

Article Biochemistry & Molecular Biology

Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway

Sansana Sawasdikosol et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation

R. Arnold et al.

CELL DEATH AND DIFFERENTIATION (2007)

Review Biochemistry & Molecular Biology

Cyclooxygenases and lipoxygenases in prostate and breast cancers

Daotai Nie

FRONTIERS IN BIOSCIENCE (2007)

Article Genetics & Heredity

A distinct inflammatory gene expression profile in patients with psoriatic arthritis

A. K. Stoeckman et al.

GENES AND IMMUNITY (2006)

Article Biochemistry & Molecular Biology

Activation or suppression of NFκB by HPK1 determines sensitivity to activation-induced cell death

D Brenner et al.

EMBO JOURNAL (2005)

Article Multidisciplinary Sciences

The protein kinase complement of the human genome

G Manning et al.

SCIENCE (2002)

Article Biochemistry & Molecular Biology

Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling

P Ling et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)