期刊
CURRENT OPINION IN CHEMICAL BIOLOGY
卷 33, 期 -, 页码 74-80出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2016.06.003
关键词
-
资金
- University of California, Berkeley
- NIH [R00NS078561]
- Brain Research Foundation
- Hellman Foundation
Voltage imaging has the potential to unravel the contributions that rapid changes in membrane voltage make to cellular physiology, especially in the context of neuroscience. In particular, small molecule fluorophores are especially attractive because they can, in theory, provide fast and sensitive measurements of membrane potential dynamics. A number of classes of small molecule voltage indicators will be discussed, including dyes with improved two-photon voltage sensing, near infrared optical profiles for use in in vivo applications, and newly developed electron-transfer based indicators, or VoltageFluors, that can be tuned across a range of wavelengths to enable all-optical voltage manipulation and measurement. Limitations and a 'wish-list' for voltage indicators will also be discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据