期刊
CURRENT OPINION IN CELL BIOLOGY
卷 38, 期 -, 页码 68-73出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2016.02.012
关键词
-
类别
资金
- EPSRC
- BBSRC [BB/M003280]
- European Research Council [647186]
- European Research Council (ERC) [647186] Funding Source: European Research Council (ERC)
- Biotechnology and Biological Sciences Research Council [BB/M003280/1, BB/K009001/1] Funding Source: researchfish
- Cancer Research UK [9786, 17343] Funding Source: researchfish
- Medical Research Council [MC_CF12266] Funding Source: researchfish
- BBSRC [BB/K009001/1, BB/M003280/1] Funding Source: UKRI
While much attention has been focused on the force-generating mechanisms responsible for shaping developing embryos, less is known about the ways in which cells in animal tissues respond to mechanical stimuli. Forces will arise within a tissue as the result of processes such as local cell death, growth and division, but they can also be an indirect consequence of morphogenetic movements in neighbouring tissues or be imposed from the outside, for example, by gravity. If not dealt with, the accumulation of stress and the resulting tissue deformation can pose a threat to tissue integrity and structure. Here we follow the time-course of events by which cells and tissues return to their preferred state following a mechanical perturbation. In doing so, we discuss the spectrum of biological and physical mechanisms known to underlie mechanical homeostasis in animal tissues.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据