期刊
CURRENT OPINION IN BIOTECHNOLOGY
卷 40, 期 -, 页码 177-184出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2016.06.003
关键词
-
资金
- NIH [R01 GM069811]
- San Diego Center for Systems Biology, NIH Grant [P50 GM085764]
CRISPR-Cas9 has recently emerged as a promising system for multiplexed genome editing as well as epigenome and transcriptome perturbation. Due to its specificity, ease of use and highly modular programmable nature, it has been widely adopted for a variety of applications such as genome editing, transcriptional inhibition and activation, genetic screening, DNA localization imaging, and many more. In this review, we will discuss non-editing applications of CRISPR-Cas9 for transcriptome perturbation, metabolic engineering, and synthetic biology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据