4.3 Article

Dietary Exposure to Acrylamide and Associated Health Risks for the Korean Population

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MDPI
DOI: 10.3390/ijerph17207619

关键词

acrylamide; food products; dietary exposure; risk assessment; margin of exposure

资金

  1. Korea Food and Drug Administration [11162KFDA041]
  2. Korea Food Research Institute [E0192101-02]

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The aim of the study was to estimate the dietary exposure to acrylamide (AA) from the consumption of various processed food and to assess the associated health risks in different age groups in Korea. Potato crisps and French fries presented the highest mean levels of AA (546 and 372 mu g/kg, respectively) followed by coffee (353 mu g/kg) and tea products (245 mu g/kg). The mean AA dietary exposure values for toddlers (<= 2 years), children (3-6 years), children (7-12 years), adolescents (13-19 years), adults (20-64 years), and seniors (>= 65 years) were estimated to be 0.15, 0.13, 0.06, 0.06, 0.08, and 0.06 mu g/kg body weight (BW)/day, respectively. Based on the benchmark dose lower confidence limit (BMDL10) of 0.18 and 0.31 mg/kg BW/day, the calculated mean and 95th percentile values for the margin of exposure were below 10,000 for the all age groups suggesting possible health concern for Koreans. Biscuits, crisps, and coffee were the primary foods contributing to dietary AA exposure among these in the Korean populations. In children, considering the health risk of AA dietary exposure, especially from biscuits and crisps, there is a need to further control and modify dietary habits to ensure lower AA exposure.

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