期刊
CURRENT OPINION IN VIROLOGY
卷 44, 期 -, 页码 154-161出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2020.08.004
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资金
- National Institutes of Health [R01AI141889]
- National Science Foundation/EPSCoR [IIA-1335423]
- State of South Dakota's Governor's Office of Economic Development
- SDSU-AES [3AH-673]
Influenza D is the only type of influenza virus that mainly affects cattle with frequent spillover to other species. Since the initial description of influenza D virus (IDV) in 2011, the virus has been found to circulate among cattle and swine populations worldwide. Research conducted during the past several years has led to an increased understanding of this novel influenza virus with bovines as a reservoir. In this review, we describe the current knowledge of epidemiology and host range of IDV followed by discussion of infection biology and animal model development for IDV. Finally, we review progress towards understanding of the pathogenesis and host response of IDV as well as developing preventive vaccines for IDV.
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