4.7 Article

Association of Maternal Plasma Total Cysteine and Growth among Infants in Nepal: A Cohort Study

期刊

NUTRIENTS
卷 12, 期 9, 页码 -

出版社

MDPI
DOI: 10.3390/nu12092849

关键词

amino acid; metabolism; tCys; malnutrition; weight; length; child; stunting; wasting; Asia

资金

  1. Centre of Excellence Scheme
  2. University of Bergen, Norway [223269]
  3. Innlandet Hospital Trust

向作者/读者索取更多资源

Cysteine is a semi-essential amino acid that has been positively associated with growth in children. However, transgenerational effects remain unclear. The aim of this analysis was to assess whether maternal plasma total cysteine (tCys) concentration is associated with various growth indicators in infants living in peri-urban settings in Bhaktapur, Nepal. We used data from the 561 mothers enrolled in an ongoing randomized controlled trial. We built linear regression models to evaluate the associations between maternal tCys and birth weight, length-for-age Z-scores (LAZ) and weight-for-length Z-scores (WLZ) at birth and six months of age. Maternal tCys was inversely associated with birth weight among boys after adjusting for confounders (p< 0.05). In addition, there was a negative association between maternal tCys and LAZ at birth (p< 0.01). No associations between maternal tCys and the other anthropometric indicators were found significant, although there was a tendency for maternal tCys to be associated positively with WLZ at birth among girls (p< 0.10). This is a first study evaluating transgenerational relation of tCys on growth in infants. Further, larger and more comprehensive studies are needed to determine if and how maternal tCys alters child growth.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据