期刊
NUTRIENTS
卷 12, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/nu12103189
关键词
vitamin D; sarcopenia; atrophy; skeletal muscle; gene regulation; nuclear receptor
资金
- Japanese Ministry of Education, Culture, Sports, Science, and Technology (MEXT, Tokyo)
- Japan Dairy Association (J-milk)
Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of body weight, plays important roles in exercise and energy expenditure. In the elderly, there is often a progressive decline in skeletal muscle mass and function, a condition known as sarcopenia, which can lead to bedridden conditions, wheelchair confinement as well as reducing the quality of life (QOL). In developed countries with aging populations, the prevention and management of sarcopenia are important for the improvement of health and life expectancy in these populations. Recently, vitamin D, a fat-soluble vitamin, has been attracting attention due to its importance in sarcopenia. This review will focus on the effects of vitamin D deficiency and supplementation on sarcopenia.
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