期刊
JOURNAL OF COSMETIC DERMATOLOGY
卷 19, 期 11, 页码 2805-2811出版社
WILEY
DOI: 10.1111/jocd.13696
关键词
cosmeticeuticals; microparticles; nanoparticles
类别
资金
- Al-Ahliyya Amman University, Faculty of Allied Medical Sciences, Cosmetic Science Department
Background Poly lactic acid and its copolymers are considered to be the preferred substrates for drug delivery devices. Poly lactic acid is a biocompatible, biodegradable and nontoxic polymer. It was approved by Food and Drug Administration and thought to be among the most attractive polymeric candidates intended for controlling drug delivery. It was utilized for the development of devices for the delivery of small molecules, proteins, genes, vaccines, anticancer drugs, and macromolecules. Objectives and methods This manuscript lists the different techniques for synthesizing poly lactic acid-based nano and microparticles such as emulsion-based methods, precipitation-based methods, direct compositing methods, in situ forming micro-particles, and microfluidic technique. Conclusions In addition, it describes the application and use of poly lactic acid in biomedical and cosmetic delivery systems.
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