期刊
ACS CATALYSIS
卷 10, 期 19, 页码 10905-10913出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.0c03014
关键词
heterocycles; cycloaddition; dearomatization; site selectivity; stereoselectivity
资金
- National Research Foundation of Korea (NRF) - Korean government [NRF-2019R1A2C1087134, NRF-2019R1A4A2001440]
- Institute for Basic Scienc in Korea [IBS-R10-D1]
- GRRC program of Gyeonggi Province [GRRCKyungHee2017-A01]
- National Research Foundation of Korea [4199990213848] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Copper-catalyzed [5 + 1] cycloadditions of N-aromatic zwitterions have been accomplished by chelation-assisted 1,2-dearomative addition of electron-deficient terminal alkynes. The unique modular skeleton of pyrazino[1,2-a]quinoline could be obtained from the regio- and stereoselective cascade annulation process, which was supported by computational studies. Further, an asymmetric variant of the developed strategy has been successfully extended for enabling access to optically enriched six-member cyclic systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据