4.5 Article

Predicting target proteins for drug candidate compounds based on drug-induced gene expression data in a chemical structure-independent manner

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Open TG-GATEs: a large-scale toxicogenomics database

Yoshinobu Igarashi et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Genetics & Heredity

Systematic evaluation of connectivity map for disease indications

Jie Cheng et al.

GENOME MEDICINE (2014)

Article Biochemical Research Methods

Toxygates: interactive toxicity analysis on a hybrid microarray and linked data platform

Johan Nystroem-Persson et al.

BIOINFORMATICS (2013)

Review Pharmacology & Pharmacy

Transcriptional data: a new gateway to drug repositioning?

Francesco Iorio et al.

DRUG DISCOVERY TODAY (2013)

Article Biochemistry & Molecular Biology

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Wanjuan Yang et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

Integrated Analysis of Drug-Induced Gene Expression Profiles Predicts Novel hERG Inhibitors

Joseph J. Babcock et al.

PLOS ONE (2013)

Article Biochemical Research Methods

Drug target prediction using adverse event report systems: a pharmacogenomic approach

Masataka Takarabe et al.

BIOINFORMATICS (2012)

Article Biochemistry & Molecular Biology

ChEMBL: a large-scale bioactivity database for drug discovery

Anna Gaulton et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biotechnology & Applied Microbiology

How were new medicines discovered?

David C. Swinney et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Biochemistry & Molecular Biology

The Sequence Read Archive

Rasko Leinonen et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Biochemical Research Methods

Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework

Yoshihiro Yamanishi et al.

BIOINFORMATICS (2010)

Article Biochemistry & Molecular Biology

KEGG for representation and analysis of molecular networks involving diseases and drugs

Minoru Kanehisa et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Multidisciplinary Sciences

Discovery of drug mode of action and drug repositioning from transcriptional responses

Francesco Iorio et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemical Research Methods

Drug-Induced Regulation of Target Expression

Murat Iskar et al.

PLOS COMPUTATIONAL BIOLOGY (2010)

Article Biochemical Research Methods

Supervised prediction of drug-target interactions using bipartite local models

Kevin Bleakley et al.

BIOINFORMATICS (2009)

Article Multidisciplinary Sciences

Predicting new molecular targets for known drugs

Michael J. Keiser et al.

NATURE (2009)

Article Biochemical Research Methods

Protein-ligand interaction prediction: an improved chemogenomics approach

Laurent Jacob et al.

BIOINFORMATICS (2008)

Article Biochemical Research Methods

Prediction of drug-target interaction networks from the integration of chemical and genomic spaces

Yoshihiro Yamanishi et al.

BIOINFORMATICS (2008)

Article Multidisciplinary Sciences

Drug target identification using side-effect similarity

Monica Campillos et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

DrugBank: a comprehensive resource for in silico drug discovery and exploration

David S. Wishart et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

UniProt: the Universal Protein knowledgebase

R Apweiler et al.

NUCLEIC ACIDS RESEARCH (2004)

Article Biochemistry & Molecular Biology

ArrayExpress - a public repository for microarray gene expression data at the EBI

A Brazma et al.

NUCLEIC ACIDS RESEARCH (2003)

Article Biochemical Research Methods

Robust estimators for expression analysis

E Hubbell et al.

BIOINFORMATICS (2002)

Article Chemistry, Medicinal

Development of a combined protein and pharmacophore model for cytochrome P4502C9

MJ de Groot et al.

JOURNAL OF MEDICINAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

R Edgar et al.

NUCLEIC ACIDS RESEARCH (2002)

Article Chemistry, Medicinal

A refined 3-dimensional QSAR of cytochrome P4502C9: Computational predictions of drug interactions

S Rao et al.

JOURNAL OF MEDICINAL CHEMISTRY (2000)