4.8 Article

Characterization and mitigation of gene expression burden in mammalian cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Identification of preexisting adaptive immunity to Cas9 proteins in humans

Carsten T. Charlesworth et al.

NATURE MEDICINE (2019)

Article Biochemistry & Molecular Biology

An estimate of the total number of true human miRNAs

Julia Alles et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Medicine, Research & Experimental

Advancements and Obstacles of CRISPR-Cas9 Technology in Translational Research

Liting You et al.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)

Article Multidisciplinary Sciences

A universal biomolecular integral feedback controller for robust perfect adaptation

Stephanie K. Aoki et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

Noise-reducing optogenetic negative-feedback gene circuits in human cells

Michael Tyler Guinn et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Multidisciplinary Sciences

Role of network-mediated stochasticity in mammalian drug resistance

Kevin S. Farquhar et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Evolutionary regain of lost gene circuit function

Mirna Kheir Gouda et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Biotechnology & Applied Microbiology

Engineered Cell-Based Therapeutics: Synthetic Biology Meets Immunology

Fabio Caliendo et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)

Article Biotechnology & Applied Microbiology

Optimization of a high-cell-density polyethylenimine transfection method for rapid protein production in CHO-EBNA1 cells

Matthew Stuible et al.

JOURNAL OF BIOTECHNOLOGY (2018)

Article Biotechnology & Applied Microbiology

Engineered promoters enable constant gene expression at any copy number in bacteria

Thomas H. Segall-Shapiro et al.

NATURE BIOTECHNOLOGY (2018)

Article Biochemical Research Methods

Burden-driven feedback control of gene expression

Francesca Ceroni et al.

NATURE METHODS (2018)

Article Multidisciplinary Sciences

Engineering modular intracellular protein sensor-actuator devices

Velia Siciliano et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Synthetic control systems for high performance gene expression in mammalian cells

Gabriele Lillacci et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Computer Science, Artificial Intelligence

Scaling up genetic circuit design for cellular computing: advances and prospects

Yiyu Xiang et al.

NATURAL COMPUTING (2018)

Article Multidisciplinary Sciences

The impact of microRNAs on transcriptional heterogeneity and gene co-expression across single embryonic stem cells

Gennaro Gambardella et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion

Thomas Beuchert Kallehauge et al.

SCIENTIFIC REPORTS (2017)

Article Biochemical Research Methods

Resource Competition Shapes the Response of Genetic Circuits

Yili Qian et al.

ACS SYNTHETIC BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law

M. Carbonell-Ballestero et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Microbiology

Overloaded and stressed: whole-cell considerations for bacterial synthetic biology

Olivier Borkowski et al.

CURRENT OPINION IN MICROBIOLOGY (2016)

Article Multidisciplinary Sciences

Molecular circuits for dynamic noise filtering

Christoph Zechner et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

β-cell-mimetic designer cells provide closed-loop glycemic control

Mingqi Xie et al.

SCIENCE (2016)

Article Cell Biology

The Cost of Protein Production

Moshe Kafri et al.

CELL REPORTS (2016)

Article Biophysics

Isocost Lines Describe the Cellular Economy of Genetic Circuits

Andras Gyorgy et al.

BIOPHYSICAL JOURNAL (2015)

Article Cell & Tissue Engineering

Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches

Kenji Miki et al.

CELL STEM CELL (2015)

Article Biotechnology & Applied Microbiology

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery

Liliana Wroblewska et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemical Research Methods

Quantifying cellular capacity identifies gene expression designs with reduced burden

Francesca Ceroni et al.

NATURE METHODS (2015)

Article Multidisciplinary Sciences

Mechanistic links between cellular trade-offs, gene expression, and growth

Andrea Y. Weisse et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemical Research Methods

A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly

Michael E. Lee et al.

ACS SYNTHETIC BIOLOGY (2015)

Article Biochemistry & Molecular Biology

miR-Synth: a computational resource for the design of multi-site multi-target synthetic miRNAs

Alessandro Lagana et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemical Research Methods

MicroRNA-Based Single-Gene Circuits Buffer Protein Synthesis Rates against Perturbations

Timothy J. Strovas et al.

ACS SYNTHETIC BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

A Mini-intronic Plasmid (MIP): A Novel Robust Transgene Expression Vector In Vivo and In Vitro

Jiamiao Lu et al.

MOLECULAR THERAPY (2013)

Review Cell Biology

Diversifying microRNA sequence and function

Stefan L. Ameres et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

Transferring a synthetic gene circuit from yeast to mammalian cells

Dmitry Nevozhay et al.

NATURE COMMUNICATIONS (2013)

Article Multidisciplinary Sciences

miRNAs confer phenotypic robustness to gene networks by suppressing biological noise

Velia Siciliano et al.

NATURE COMMUNICATIONS (2013)

Article Physics, Multidisciplinary

Competition for Catalytic Resources Alters Biological Network Dynamics

Yannick Rondelez

PHYSICAL REVIEW LETTERS (2012)

Article Biochemistry & Molecular Biology

Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template

Leonidas Bleris et al.

MOLECULAR SYSTEMS BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Queueing up for enzymatic processing: correlated signaling through coupled degradation

Natalie A. Cookson et al.

MOLECULAR SYSTEMS BIOLOGY (2011)

Article Biochemistry & Molecular Biology

Experimental strategies for microRNA target identification

Daniel W. Thomson et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Multidisciplinary Sciences

Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells

Zhen Xie et al.

SCIENCE (2011)

Article Multidisciplinary Sciences

Systematic Comparison of Constitutive Promoters and the Doxycycline-Inducible Promoter

Jane Yuxia Qin et al.

PLOS ONE (2010)

Article Multidisciplinary Sciences

Interdependence of Cell Growth and Gene Expression: Origins and Consequences

Matthew Scott et al.

SCIENCE (2010)

Article Multidisciplinary Sciences

The ground state of embryonic stem cell self-renewal

Qi-Long Ying et al.

NATURE (2008)

Article Multidisciplinary Sciences

Engineering stability in gene networks by autoregulation

A Becskei et al.

NATURE (2000)