Raman spectroscopy and gas chromatography with flame ionization detection as analysis tools in stability tests of selected synthetic psychoactive substances: 5-IT, MT-45 and 4-CMC

This publication deals with three psychoactive substances: 5-IT (1-(1H-Indol-5-yl)propan-2-amine), MT-45 (1cyclohexyl-4-(1,2-diphenylethyl)-piperazine) and 4-CMC (2-methylamino-1-para-chlorofluorophenyl-propan-1-one). These compounds are hazardous to the health of their users. They may be unstable during long and improper storage, which creates an additional risk for people who use them. Therefore, it is important to check whether this phenomenon occurs in case of these compounds. Syntheses of compounds were carried out in our laboratory. Their identity was confirmed using a wide range of spectrometric, spectroscopic and chromatographic methods. Raman spectroscopy and gas chromatography with flame ionization detection were used as analysis tools in stability tests. The impact of storage time (up to 3 months) and temperature conditions (-20 degrees C, +4 degrees C, RT, +40 degrees C) on samples was examined.