Controversies in the management of twin pregnancy

Despite many advances in antenatal care, twin pregnancies still experience more adverse outcomes, in particular perinatal morbidity and mortality. They also pose a multitude of challenges and controversies, as outlined in this Review. Moreover, they are less likely to be included in clinical trials. Many issues on classification and management remain under debate. Efforts in standardizing diagnostic criteria, monitoring protocols, management and outcome reporting are likely to reduce their perinatal risks. The top 10 most important research uncertainties related to multiple pregnancies have been identified by both clinicians and patients. More robust research in the form of randomized trials and large well-conducted prospective cohort studies is needed to address these controversies. (c) 2020 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.

Automated summary

Despite advances in antenatal care, twin pregnancies still face higher risks during the perinatal period, along with challenges and controversies in classification and management. Identifying and addressing the top 10 research uncertainties related to multiple pregnancies is crucial for improving outcomes and reducing risks. More robust research, including randomized trials and large prospective cohort studies, is needed to address these controversies.