期刊
ULTRASOUND IN MEDICINE AND BIOLOGY
卷 46, 期 9, 页码 2245-2253出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2020.04.016
关键词
Pancreatic adenocarcinoma; Contrast-enhanced ultrasonography (CEUS); Contrast-enhanced computed tomography (CECT); Early diagnosis; Small pancreatic cancer
The purpose of this retrospective study is to evaluate the effectiveness of contrast-enhanced ultrasonography for the characterization of small and early stage pancreatic adenocarcinoma. Contrast-enhanced ultrasonography and contrast-enhanced computed tomography (CT) were performed in 200 cases, with pancreatic hypoechoic regions detected with ultrasonography. Assuming that hypo-enhancement was indicative of pancreatic adenocarcinoma, the sensitivity of each imaging modality was calculated. The sensitivities of contrast-enhanced ultrasonography and contrast-enhanced CT to characterize adenocarcinoma were 97.0% and 77.0% (p < 0.0001) for all 100 adenocarcinoma cases, 100% and 76.7% (p = 0.0016) for 43 small (<= 20 mm) cancers, 100% and 58.3% (p = 0.0253) for 12 smaller (<= 10 mm) cancers and 100% and 72.2% (p = 0.0016) for 36 stage IA cancers, respectively. The sensitivity of contrast-enhanced ultrasonography was sufficiently high and significantly superior to that of contrast-enhanced CT. Contrast-enhanced ultrasonography is a sensitive tool for selecting highly possible pancreatic adenocarcinoma lesions without overlooking early stage tiny adenocarcinomas among a large number of hypoechoic lesions detected with ultrasonography. (C) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
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