期刊
TRENDS IN PLANT SCIENCE
卷 26, 期 1, 页码 23-32出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tplants.2020.07.015
关键词
-
资金
- Japan Society for Science and Technology [17K07747]
- Harold R. Burton Endowed Professorship
- National Science Foundation [1355438]
Plants produce structurally diverse specialized metabolites in response to environmental stresses, with the AP2/ERF family of transcription factors playing key roles in regulating biosynthesis. Research has shown that some ERF genes occur in clusters on chromosomes, with jasmonate-responsive ERF gene clusters controlling the biosynthesis of important metabolites.
Plants produce structurally diverse specialized metabolites, including bioactive alkaloids and terpenoids, in response to biotic and abiotic environmental stresses. The APETALA2/ETHYLENE RESPONSE FACTOR (AP2/ERF) family of transcription factors (TFs) play key roles in regulating biosynthesis of specialized metabolites. Increasing genomic and functional evidence shows that a subset of the ERF genes occurs in clusters on the chromosomes. These jasmonate-responsive ERF TF gene clusters control the biosynthesis of many important metabolites, from natural products, such as nicotine and steroidal glycoalkaloids (SGAs), to pharmaceuticals, such as artemisinin, vinblastine, and vincristine. Here, we review the function, regulation, and evolution of ERF clusters and highlight recent advances in understanding the distinct roles of clustered ERF genes and their possible application in metabolic engineering.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据