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Antiparasitics in Animal Health: Quo Vadis?

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TRENDS IN PARASITOLOGY
卷 37, 期 1, 页码 77-89

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ELSEVIER SCI LTD
DOI: 10.1016/j.pt.2020.09.004

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Antiparasitics acting on endo- or ectoparasites represent the second largest segment of the global animal health market, but few novel antiparasitic agents have been introduced in recent years. To address resistance issues, there is a clear need for novel antiparasitics with new modes/mechanisms of action.
Antiparasitics acting on endo- or ectoparasites represent the second largest segment of the global animal health market, accounting for 23% of market share. However, relatively few novel antiparasitic agents have been introduced into the market during recent decades. One exception, and a groundbreaking 21st century success story, are the isoxazolines, whose full potential has not yet been entirely explored. Unfortunately, resistance issues are present across most parasitic diseases, which generates a clear market need for novel resistance-breaking antiparasitics with new modes/mechanisms of action. Recent advances in science and technologies strongly suggest that the time is right to invest in new modalities such as parasitic vaccines or in environmentally friendly interventions.

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