Domestic dog origin ofCarnivore Protoparvovirus 1infection in a rescued free-ranging guina (Leopardus guigna)in Chile

Carnivore protoparvovirus 1is one of the most important pathogens affecting both wild and domestic carnivores. Here, we reported the genetic characterization of canine parvovirus (CPV-2) strains from a rescued guina (Leopardus guigna) and domestic dogs from Chile. Guina strain was classified as CPV-2c, and phylogenetic analysis of the complete coding genome showed that the guina CPV-2c strain shares a recent common ancestor with Chilean domestic dogs' strains. These viruses showed >99% identity and exhibited three changes in the NS1 protein (V596A, E661K and L582F). This is the first detection and genetic characterization of CPV-2c infection in guina worldwide, and one of the few comparative studies that show the source of infection was domestic dogs. The current findings highlight the fact that guina is a susceptible species to protoparvovirus infection and that domestic dogs represent an important threat to its conservation. The CPV-2 cross-species transmission between domestic dogs and guina should be taken into account for protection programmes of this endangered species.

Automated summary

This study reported the genetic characterization of CPV-2 strains from a rescued guina and domestic dogs in Chile, showing a recent common ancestor between them. It is the first detection of CPV-2c infection in guina worldwide, with domestic dogs likely being the source of infection.