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Functional candidate genes in age-related macular degeneration: Significant association with VEGF, VLDLR, and LRP6
JL Haines et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Psychosocial effects of age-related macular degeneration
K. Berman et al.
INTERNATIONAL PSYCHOGERIATRICS (2006)
The antioxidant function of the p53 tumor suppressor
AA Sablina et al.
NATURE MEDICINE (2005)
Flavonoids protect retinal ganglion cells from oxidative stress-induced death
P Maher et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
The role of Keap1 in cellular protective responses
AT Dinkova-Kostova et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2005)
Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy
CA Curcio et al.
EXPERIMENTAL EYE RESEARCH (2005)
FOXO transcription factors at the interface between longevity and tumor suppression
EL Greer et al.
ONCOGENE (2005)
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
RD Guzy et al.
CELL METABOLISM (2005)
Age-related macular degeneration: economic burden and value-based medicine analysis
MM Brown et al.
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE (2005)
Complement factor H variant increases the risk of age-related macular degeneration
JL Haines et al.
SCIENCE (2005)
Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice
M Tanito et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
M Kobayashi et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Understanding the odd science of aging
TBL Kirkwood
CELL (2005)
Reactive oxygen and nitrogen species: Friends or foes?
DB Zorov et al.
BIOCHEMISTRY-MOSCOW (2005)
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina
JP SanGiovanni et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2005)
Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10
J Feher et al.
OPHTHALMOLOGICA (2005)
Glutathione, stress responses, and redox signaling in lung inflammation
I Rahman et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Smoking and age-related macular degeneration: a review of association
J Thornton et al.
EYE (2005)
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
AV Budanov et al.
SCIENCE (2004)
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2
A Kobayashi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
XQ Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Risk factors for incident age-related macular degeneration - Pooled findings from 3 continents
SC Tomany et al.
OPHTHALMOLOGY (2004)
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
T Rangasamy et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Melatonin, human aging, and age-related diseases
M Karasek
EXPERIMENTAL GERONTOLOGY (2004)
Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase
GP Sorescu et al.
CIRCULATION RESEARCH (2004)
The Women's Health Initiative dietary modification trial: Overview and baseline characteristics of participants
C Ritenbaugh et al.
ANNALS OF EPIDEMIOLOGY (2003)
Mitotropic compounds for the treatment of age-related macular degeneration - The metabolic approach and a pilot study
J Feher et al.
OPHTHALMOLOGICA (2003)
Progression of age-related macular degeneration - Association with body mass index, waist circumference, and waist-hip ratio
JM Seddon et al.
ARCHIVES OF OPHTHALMOLOGY (2003)
PA26 is a candidate gene for heterotaxia in humans:: identification of a novel PA26-related gene family in human and mouse
H Peeters et al.
HUMAN GENETICS (2003)
The association of cardiovascular disease with the lone-term incidence of ageorelated maculopathy - The Beaver Dam eye study
R Klein et al.
OPHTHALMOLOGY (2003)
Progression of age-related macular degeneration - Association with dietary fat, transunsaturated fat, nuts, and fish intake
JM Seddon et al.
ARCHIVES OF OPHTHALMOLOGY (2003)
Long term dietary supplementation with zeaxanthin reduces photoreceptor death in light-damaged Japanese quail
LR Thomson et al.
EXPERIMENTAL EYE RESEARCH (2002)
The role of apoptosis in age-related macular degeneration
JL Dunaief et al.
ARCHIVES OF OPHTHALMOLOGY (2002)
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
GJPL Kops et al.
NATURE (2002)
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability
AV Budanov et al.
ONCOGENE (2002)
Biochemical functions of coenzyme Q10
FL Crane
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2001)
An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration
GS Hageman et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2001)
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss - AREDS Report No. 8
A Kassoff et al.
ARCHIVES OF OPHTHALMOLOGY (2001)
Dietary fat and risk for advanced age-related macular degeneration
JM Seddon et al.
ARCHIVES OF OPHTHALMOLOGY (2001)
Antioxidant effect of flavonoids after ascorbate/Fe2+-induced oxidative stress in cultured retinal cells
FM Areias et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Does coenzyme Q(10) play a role in opposing oxidative stress in patients with age-related macular degeneration?
MA Blasi et al.
OPHTHALMOLOGICA (2001)
Coenzyme Q is an obligatory cofactor for uncoupling protein function
KS Echtay et al.
NATURE (2000)
Mitochondrial bioenergetics in aging
G Lenaz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2000)
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
RF Mullins et al.
FASEB JOURNAL (2000)