期刊
SURFACE & COATINGS TECHNOLOGY
卷 405, 期 -, 页码 -出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.surfcoat.2020.126521
关键词
Biomedical Mg implants; Corrosion; Conversion coatings; Non-conversion coatings; Osseoconductive functionality; In vivo stability
The development of magnesium alloys for biomedical applications requires the use of protective coatings and the development of advanced alloy formulations with enhanced corrosion resistance. Research focuses on improving the biostability of magnesium alloys in simulated body fluid and in vivo environments, mainly through surface coatings and osseoconductive coatings.
Several magnesium alloys are increasingly used for a variety of biomedical applications, owing to their favorable mechanical and biomedical properties. However, in vivo corrosion in aqueous environment including Cl ion-rich extracellular fluid (ECF) requires the application of protective coatings as well as the development of advanced alloy formulations with increased corrosion resistance and uniform, non-localized dissolution modes. This contribution reviews recent promising approaches towards improved biostability of Mg alloys during in vitro contact with simulated body fluid (SBF) as well as in vivo exposure to ECF. Emphasis is being put on surface coatings for corrosion protection as well as on functional osseoconductive coatings that stimulate tissue ingrowth.
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