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CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma
Masanobu Tsubaki et al.
CYTOKINE (2011)
Statins and prostate cancer: Molecular and clinical aspects
Georgios Papadopoulos et al.
EUROPEAN JOURNAL OF CANCER (2011)
Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma
Masashi Yanae et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)
PI3Kinase signaling in glioblastoma
M. M. Lino et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
Anticancer Efficacy of Simvastatin on Prostate Cancer Cells and Tumor Xenografts Is Associated with Inhibition of Akt and Reduced Prostate-Specific Antigen Expression
Samith T. Kochuparambil et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Simvastatin Therapy Reduces Prooxidant-Antioxidant Balance: Results of a Placebo-Controlled Cross-Over Trial
Seyyed M. R. Parizadeh et al.
LIPIDS (2011)
Statin use and cancer risk: a comprehensive review
Denise M. Boudreau et al.
EXPERT OPINION ON DRUG SAFETY (2010)
Inhibition of C-reactive protein induced expression of matrix metalloproteinases by atorvastatin in THP-1 cells
Nitin Mahajan et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2010)
Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion
Shuh Narumiya et al.
CANCER AND METASTASIS REVIEWS (2009)
Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression
Hongli Liu et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Combined Treatment of gamma-Tocotrienol with Statins Induce Mammary Tumor Cell Cycle Arrest in G1
Vikram B. Wali et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2009)
EFFECT OF SIMVASTATIN ON GLIOMA CELL PROLIFERATION, MIGRATION, AND APOPTOSIS
Hongtao Wu et al.
NEUROSURGERY (2009)
Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells
Olorunseun O. Ogunwobi et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2008)
Statin induces apoptosis and cell growth arrest in prostate cancer cells
Ashraful Hoque et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)
Statin-induced inhibition of MCF-7 breast cancer cell proliferation is related to cell cycle arrest and apoptotic and necrotic cell death mediated by an enhanced oxidative stress
Claudia A. Sanchez et al.
CANCER INVESTIGATION (2008)
Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice
Soo-Jeong Cho et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Blockade of the RhoA-JNK-c-Jun-MMP2 Cascade by Atorvastatin Reduces Osteosarcoma Cell Invasion
Olivia Fromigue et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation
Kamala P. Sundararaj et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status
Catia Cemeus et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
David Y. L. Chan et al.
JOURNAL OF NEURO-ONCOLOGY (2008)
Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells
Guillaume Sarrabayrouse et al.
NEOPLASIA (2007)
Comparative evaluation of the effects of statins on human stem and cancer cells in vitro
Kalarnegarn Gauthaman et al.
REPRODUCTIVE BIOMEDICINE ONLINE (2007)
Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation
Mi-Hee Lee et al.
STEM CELLS (2007)
Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK
Meral Koyuturk et al.
CANCER LETTERS (2007)
Regulation of the actin cytoskeleton in cancer cell migration and invasion
Hideki Yamaguchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Combination of lovastatin and X-irradiation decreases clonogenicity, cell number, and induces changes in the cell cycle of U87 human malignant glioma cells
D Gabrys et al.
RADIOTHERAPY AND ONCOLOGY (2006)
Statins of different brain penetrability differentially affect CSFPLTP activity
Simona Vuletic et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2006)
Anti-angiogenic and anti-inflammatory effects of statins:: Relevance to anti-cancer therapy
J Dulak et al.
CURRENT CANCER DRUG TARGETS (2005)
Cell cycle arrest and apoptosis induction in hepatocellular carcinoma cells by HMG-CoA reductase inhibitors.: Synergistic antiproliferative action with ligands of the peripheral benzodiazepine receptor
AP Sutter et al.
JOURNAL OF HEPATOLOGY (2005)
Statin-induced apoptosis linked with membrane farnesylated Ras small G protein depletion, rather than geranylated Rho protein
S Matzno et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2005)
Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells
P Cafforio et al.
CARCINOGENESIS (2005)
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
T Kanzawa et al.
CELL DEATH AND DIFFERENTIATION (2004)
Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells
ZH Jiang et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Simvastatin induces proliferation inhibition and apoptosis in C6 glioma cells via c-jun N-terminal kinase
M Koyuturk et al.
NEUROSCIENCE LETTERS (2004)
Simvastatin induces apoptosis of B-CLL cells by activation of mitochondrial caspase 9
D Chapman-Shimshoni et al.
EXPERIMENTAL HEMATOLOGY (2003)
Migration, proliferation, and invasion of human glioma cells following treatment with simvastatin
J Gliemroth et al.
NEUROSURGICAL REVIEW (2003)
Inhibition of migration of human glioblastoma cells by cerivastatin in association with focal adhesion kinase (FAK)
S Obara et al.
CANCER LETTERS (2002)
Statins have biphasic effects on angiogenesis
M Weis et al.
CIRCULATION (2002)
Inhibitors of HMG-CoA reductase sensitize human smooth muscle cells to Fas-ligand and cytokine-induced cell death
AC Knapp et al.
ATHEROSCLEROSIS (2000)
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