ZIKV viral proteins and their roles in virus-host interactions

The re-emergence of Zika virus (ZIKV) and its associated neonatal microcephaly and Guillain-Barre syndrome have led the World Health Organization to declare a global health emergency. Until today, many related studies have successively reported the role of various viral proteins of ZIKV in the process of ZIKV infection and pathogenicity. These studies have provided significant insights for the treatment and prevention of ZIKV infection. Here we review the current research advances in the functional characterization of the interactions between each ZIKV viral protein and its host factors.

Automated summary

The re-emergence of Zika virus has led to a global health emergency due to its association with neonatal microcephaly and Guillain-Barre syndrome. Recent studies have identified the roles of various viral proteins in Zika virus infection, providing insights for treatment and prevention strategies. Research on the interactions between Zika virus proteins and host factors has advanced our understanding of the virus's pathogenicity.