Synthesis of Pyrrolo[2,1-c][1,4]oxazine-1,6,7-triones by the Reaction of 3-Methylenemorpholin-2-ones with Oxalyl Chloride

(Z)-3-(2-Aryl-2-oxoethylidene)morpholin-2-ones were synthesized by the reaction of aroylpyruvic acids with ethanolamine or 2-propanolamine. The products reacted with oxalyl chloride to form 8-aroyl-3,4-dihydropyrrolo[2,1-c][1,4]oxazin-1,6,7(1H)-triones.