相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Type I fatty acid synthase trapped in the octanoyl-bound state
Alexander Rittner et al.
PROTEIN SCIENCE (2020)
Gating mechanism of elongating β-ketoacyl-ACP synthases
Jeffrey T. Mindrebo et al.
NATURE COMMUNICATIONS (2020)
Structural and dynamical rationale for fatty acid unsaturation in Escherichia coli
Greg J. Dodge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase
Fa Zhang et al.
BIOCHEMISTRY (2019)
Molecular basis for interactions between an acyl carrier protein and a ketosynthase
Jacob C. Milligan et al.
NATURE CHEMICAL BIOLOGY (2019)
Enhanced Production of Fatty Acid Ethyl Ester with Engineered fabHDG Operon in Escherichia coli
Ziaur Rahman et al.
MICROORGANISMS (2019)
Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains
Maja Klaus et al.
ACS CHEMICAL BIOLOGY (2019)
Active site labeling of fatty acid and polyketide acyl-carrier protein transacylases
Tony D. Davis et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2019)
Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering
Alexander Rittner et al.
ACS CHEMICAL BIOLOGY (2018)
Acyl-coenzyme A:(holo-acyl carrier protein) transacylase enzymes as templates for engineering
Aaron M. Marcella et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2018)
Biophysical and in silico interaction studies of aporphine alkaloids with Malonyl-CoA: ACP transacylase (FabD) from drug resistant Moraxella catarrhalis
Vijay Kumar et al.
BIOCHIMIE (2018)
Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis
Akimasa Miyanaga et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Elucidation of the crystal structure of FabD from the multidrug-resistant bacterium Acinetobacter baumannii
Woo Cheol Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Biochemical and biophysical characterization of 1,4-naphthoquinone as a dual inhibitor of two key enzymes of type II fatty acid biosynthesis from Moraxella catarrhalis
Vijay Kumar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2018)
Analysis and engineering of substrate shuttling by the acyl carrier protein (ACP) in fatty acid synthases (FASs)
Emanuele Rossini et al.
CHEMICAL COMMUNICATIONS (2018)
The architectures of iterative type I PKS and FAS
Dominik A. Herbst et al.
NATURAL PRODUCT REPORTS (2018)
Trapping interactions between catalytic domains and carrier proteins of modular biosynthetic enzymes with chemical probes
Andrew M. Gulick et al.
NATURAL PRODUCT REPORTS (2018)
Efficient de novo synthesis of resveratrol by metabolically engineered Escherichia coli
Junjun Wu et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2017)
Engineering fatty acid synthases for directed polyketide production
Jan Gajewski et al.
NATURE CHEMICAL BIOLOGY (2017)
Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
Jan Gajewski et al.
NATURE COMMUNICATIONS (2017)
The R117A variant of the Escherichia coli transacylase FabD synthesizes novel acyl-(acyl carrier proteins)
Aaron M. Marcella et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)
Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain
Jesus F. Barajas et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
In Vitro Investigation of Crosstalk between Fatty Acid and Polyketide Synthases in the Andrimid Biosynthetic Assembly Line
Fumihiro Ishikawa et al.
CHEMBIOCHEM (2016)
Evolutionary distinctiveness of fatty acid and polyketide synthesis in eukaryotes
Gurjeet S. Kohli et al.
ISME JOURNAL (2016)
Atomic-Level Characterization of the Chain-Flipping Mechanism in Fatty-Acids Biosynthesis
Francesco Colizzi et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2016)
Recent advances in the biosynthesis of unusual polyketide synthase substrates
Lauren Ray et al.
NATURAL PRODUCT REPORTS (2016)
Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology
Kira J. Weissman
NATURAL PRODUCT REPORTS (2016)
Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis
Akimasa Miyanaga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Geometry of guanidinium groups in arginines
Maura Malinska et al.
PROTEIN SCIENCE (2016)
Using Modern Tools To Probe the Structure-Function Relationship of Fatty Acid Synthases
Kara Finzel et al.
CHEMBIOCHEM (2015)
Probing the Substrate Specificity and Protein-Protein Interactions of the E. coli Fatty Acid Dehydratase, FabA
Kara Finzel et al.
CHEMISTRY & BIOLOGY (2015)
Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis
Jaclyn M. Winter et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Evolution of chemical diversity by coordinated gene swaps in type II polyketide gene clusters
Maureen E. Hillenmeyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal
John E. Cronan
BIOCHEMICAL JOURNAL (2014)
Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems
Martin Grininger
CURRENT OPINION IN STRUCTURAL BIOLOGY (2014)
Trapping the dynamic acyl carrier protein in fatty acid biosynthesis
Chi Nguyen et al.
NATURE (2014)
A Polyketide Synthase Acyltransferase Domain Structure Suggests a Recognition Mechanism for Its Hydroxymalonyl-Acyl Carrier Protein Substrate
Hyunjun Park et al.
PLOS ONE (2014)
Mechanism and Specificity of an Acyltransferase Domain from a Modular Polyketide Synthase
Briana J. Dunn et al.
BIOCHEMISTRY (2013)
Engineering the acyltransferase substrate specificity of assembly line polyketide synthases
Briana J. Dunn et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2013)
Expanding the Fluorine Chemistry of Living Systems Using Engineered Polyketide Synthase Pathways
Mark C. Walker et al.
SCIENCE (2013)
Improving fatty acid production in escherichia coli through the overexpression of malonyl coA-Acyl carrier protein transacylase
Xiujun Zhang et al.
BIOTECHNOLOGY PROGRESS (2012)
Structure and Mechanism of the trans-Acting Acyltransferase from the Disorazole Synthase
Fong T. Wong et al.
BIOCHEMISTRY (2011)
Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterases
Xiujun Zhang et al.
METABOLIC ENGINEERING (2011)
Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design
Guenter Pappenberger et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Mechanism-based crosslinking as a gauge for functional interaction of modular synthases
Andrew S. Worthington et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Plasmodium falciparum acyl carrier protein crystal structures in disulfide-linked and reduced states and their prevalence during blood stage growth
John R. Gallagher et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2010)
Structure and function of eukaryotic fatty acid synthases
Timm Maier et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2010)
Structure and Malonyl CoA-ACP Transacylase Binding of Streptomyces coelicolor Fatty Acid Synthase Acyl Carrier Protein
Christopher J. Arthur et al.
ACS CHEMICAL BIOLOGY (2009)
The Biosynthetic Logic of Polyketide Diversity
Christian Hertweck
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein
Simon E. Evans et al.
CHEMBIOCHEM (2008)
Probing the compatibility of type II ketosynthase-carrier protein partners
Andrew S. Worthington et al.
CHEMBIOCHEM (2008)
Molecular Dynamics Simulations of the Apo-, Holo-, and Acyl-forms of Escherichia coli Acyl Carrier Protein
David I. Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT)
Hemza Ghadbane et al.
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2007)
Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein
Liang Zhang et al.
PROTEIN SCIENCE (2007)
Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs
Alok Kumar Sharma et al.
BIOCHEMISTRY (2006)
Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography
Christian Oefner et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Characterization and inhibitor discovery of one novel malonyl-CoA:: Acyl carrier protein transacylase (MCAT) from Helicobacter pylori
WZ Liu et al.
FEBS LETTERS (2006)
One-pot chemo-enzymatic synthesis of reporter-modified proteins
AS Worthington et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
Chemobiosynthesis of novel 6-deoxyerythronolide B analogues by mutation of the loading module of 6-deoxyerythronolide B synthase 1
S Murli et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2005)
A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD)
J Molnos et al.
ANALYTICAL BIOCHEMISTRY (2003)
Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase
AT Keatinge-Clay et al.
STRUCTURE (2003)
Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site
AE Szafranska et al.
BIOCHEMISTRY (2002)
Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations
CD Reeves et al.
BIOCHEMISTRY (2001)