Ocular Tuberculosis: More than 'Of Mice and Men'

Tuberculosis (TB), caused by infection with members of theMycobacterium tuberculosis-complex, is one of the oldest known infectious disease entities, resulting in the death of millions of humans each year. It also results in a substantial degree of morbidity and mortality in animal species. Extrapulmonary TB is well recognized in humans, and the eye is one site that can be affected. Studies seeking to understand ocular TB have often relied on animal models; however, these have their limitations and may not truly reflect what happens in humans. We wish to raise awareness among ophthalmologists and vision scientists of naturally occurring cases of ocular TB in animals, namely cattle and domestic cats, and the possibilities of gaining further understanding of this presentation of TB by adopting a collaborative approach. This will hopefully improve outcomes for both human and animal patients.

Automated summary

Tuberculosis is an ancient infectious disease that causes millions of deaths each year in humans, as well as significant morbidity and mortality in animals. Ocular tuberculosis is a recognized condition in humans, but its occurrence in animals, such as cattle and domestic cats, requires further investigation in order to improve treatment outcomes.