FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update

The FlyRNAi database at the Drosophila RNAi Screening Center and Transgenic RNAi Project (DRSC/TRiP) provides a suite of online resources that facilitate functional genomics studies with a special emphasis on Drosophila melanogaster. Currently, the database provides: gene-centric resources that facilitate ortholog mapping and mining of information about orthologs in common genetic model species; reagent-centric resources that help researchers identify RNAi and CRISPR sgRNA reagents or designs; and data-centric resources that facilitate visualization and mining of transcriptomics data, protein modification data, protein interactions, and more. Here, we discuss updated and new features that help biological and biomedical researchers efficiently identify, visualize, analyze, and integrate information and data for Drosophila and other species. Together, these resources facilitate multiple steps in functional genomics workflows, from building gene and reagent lists to management, analysis, and integration of data.

Automated summary

The FlyRNAi database at DRSC/TRiP provides online resources for functional genomics studies, focusing on Drosophila melanogaster. It includes gene-centric, reagent-centric, and data-centric resources to aid in ortholog mapping, identifying RNAi and CRISPR sgRNA reagents, and visualizing transcriptomics data and protein interactions. These features help biological and biomedical researchers efficiently integrate and analyze information for Drosophila and other species in functional genomics workflows.