期刊
NEW ENGLAND JOURNAL OF MEDICINE
卷 383, 期 12, 页码 1156-1166出版社
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMra1911109
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资金
- NIAID NIH HHS [R01 AI097457, R37 AI097457, P01 AI118688] Funding Source: Medline
- NIDDK NIH HHS [U01 DK123559, UC4 DK116264] Funding Source: Medline
The immune system distinguishes between self and nonself and remembers dangerous exposures. Elaborate mechanisms control immune responses, but in some cases, the response either does not recognize the danger or causes unwanted autoinflammation. The authors review advances in developing durable immune tolerance.
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