期刊
NEUROLOGICAL SCIENCES
卷 42, 期 3, 页码 1139-1143出版社
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s10072-020-04841-4
关键词
Multiple Sclerosis; Essential Tremor; High-Intensity Focused Ultrasound Ablation; Interventional Magnetic Resonance Imaging; Stereotaxic Techniques
资金
- Italian Ministry of Education, University and Research (MIUR) [PONa3_00011]
- Italian Ministry of Health [GR-2016-02364526]
Transcranial magnetic resonance-guided focused ultrasound is a non-invasive treatment option for controlling tremors, with potential effectiveness for essential tremor in patients with multiple sclerosis. In two reported cases of patients with multiple sclerosis, this technique showed promise in controlling tremors without evidence of disease progression.
Transcranial magnetic resonance-guided focused ultrasound is a recently introduced incisionless treating option for essential tremor and tremor-dominant idiopathic Parkinson disease. There is preliminary evidence that it may result in a promising effective treatment option for other movement disorders too. Here, we report on two patients with multiple sclerosis with medication refractory debilitating essential tremor comorbidity who successfully underwent unilateral Vim tcMRgFUS thalamotomy for tremor control. Patients' clinical condition and expanded disability status scale scores showed no changes during the 1-year follow-up period with no evidence of multiple sclerosis activity or progression.
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