4.6 Editorial Material

Validation of plasma-derived small extracellular vesicles as cancer biomarkers

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NATURE REVIEWS CLINICAL ONCOLOGY
卷 17, 期 12, 页码 719-720

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NATURE RESEARCH
DOI: 10.1038/s41571-020-00433-5

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  1. NIH [R01 CA168626, U01 DE029759, SBIR 75N91019C00042]

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A role for extracellular vesicles and particles (EVPs) as cancer biomarkers has been elusive. A mass spectrometry-based comparative analysis of EVPs from individuals with or without cancer has now enabled the identification of tumour-associated protein profiles in EVPs in plasma and paired tumour tissues, validating the role of EVPs as a novel liquid biopsy approach in cancer diagnosis.

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