4.8 Review

Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Gastroenterology & Hepatology

Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma

Kenta Kawasaki et al.

GASTROENTEROLOGY (2020)

Article Oncology

Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids

Johanna F. Dekkers et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2020)

Article Biochemistry & Molecular Biology

Snake Venom Gland Organoids

Yorick Post et al.

Article Cell & Tissue Engineering

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Maarten H. Geurts et al.

CELL STEM CELL (2020)

Article Multidisciplinary Sciences

Somatic inflammatory gene mutations in human ulcerative colitis epithelium

Kosaku Nanki et al.

NATURE (2020)

Article Engineering, Biomedical

Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids

Victor Hernandez-Gordillo et al.

BIOMATERIALS (2020)

Editorial Material Gastroenterology & Hepatology

Development of a Scalable Coculture System for Gut Anaerobes and Human Colon Epithelium

Nobuo Sasaki et al.

GASTROENTEROLOGY (2020)

Article Multidisciplinary Sciences

SARS-CoV-2 productively infects human gut enterocytes

Mart M. Lamers et al.

SCIENCE (2020)

Article Multidisciplinary Sciences

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

Camilla Calandrini et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Infection of bat and human intestinal organoids by SARS-CoV-2

Zhou Jie et al.

NATURE MEDICINE (2020)

Article Gastroenterology & Hepatology

Human gastric cancer modelling using organoids

Therese Seidlitz et al.

Article Cell Biology

Developing a 3D intestinal epithelium model for livestock species

Hayley Derricott et al.

CELL AND TISSUE RESEARCH (2019)

Article Multidisciplinary Sciences

Interleukin-22 protects intestinal stem cells against genotoxic stress

Konrad Gronke et al.

NATURE (2019)

Article Biotechnology & Applied Microbiology

Tubuloids derived from human adult kidney and urine for personalized disease modeling

Frans Schutgens et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

Mouse and human urothelial cancer organoids: A tool for bladder cancer research

Jasper Mullenders et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

Chronic Chlamydia infection in human organoids increases stemness and promotes age-dependent CpG methylation

Mirjana Kessler et al.

NATURE COMMUNICATIONS (2019)

Article Cell Biology

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

Gitte Berkers et al.

CELL REPORTS (2019)

Article Cell & Tissue Engineering

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids

Benedetta Artegiani et al.

CELL STEM CELL (2019)

Review Cell Biology

Metastasis Organotropism: Redefining the Congenial Soil

Yang Gao et al.

DEVELOPMENTAL CELL (2019)

Article Biochemistry & Molecular Biology

3D model for CAR-mediated cytotoxicity using patient-derived colorectal cancer organoids

Theresa E. Schnalzger et al.

EMBO JOURNAL (2019)

Article Respiratory System

Tropism of influenza B viruses in human respiratory tract explants and airway organoids

Christine H. T. Bui et al.

EUROPEAN RESPIRATORY JOURNAL (2019)

Article Genetics & Heredity

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

Ana C. F. Bolhaqueiro et al.

NATURE GENETICS (2019)

Article Biochemistry & Molecular Biology

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Oded Kopper et al.

NATURE MEDICINE (2019)

Article Engineering, Biomedical

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

Sasan Jalili-Firoozinezhad et al.

NATURE BIOMEDICAL ENGINEERING (2019)

Article Biochemistry & Molecular Biology

Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer

Myrthe Jager et al.

GENOME RESEARCH (2019)

Article Multidisciplinary Sciences

A human liver cell atlas reveals heterogeneity and epithelial progenitors

Nadim Aizarani et al.

NATURE (2019)

Article Gastroenterology & Hepatology

Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory Cells

Laura Cook et al.

GASTROENTEROLOGY (2019)

Article Biochemistry & Molecular Biology

Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction

Bruno Martorelli Di Genova et al.

PLOS BIOLOGY (2019)

Article Biochemistry & Molecular Biology

A rectal cancer organoid platform to study individual responses to chemoradiation

Karuna Ganesh et al.

NATURE MEDICINE (2019)

Article Multidisciplinary Sciences

Self-renewing endometrial epithelial organoids of the human uterus

Harriet C. Fitzgerald et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

Long-term expanding human airway organoids for disease modeling

Norman Sachs et al.

EMBO JOURNAL (2019)

Review Gastroenterology & Hepatology

Modeling Human Digestive Diseases With CRISPR-Cas9-Modified Organoids

Masayuki Fujii et al.

GASTROENTEROLOGY (2019)

Article Gastroenterology & Hepatology

Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells

Takashi Kijima et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2019)

Article Gastroenterology & Hepatology

Human Intestinal Enteroids With Inducible Neurogenin-3 Expression as a Novel Model of Gut Hormone Secretion

Alexandra L. Chang-Graham et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2019)

Article Biochemistry & Molecular Biology

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs et al.

Article Biochemistry & Molecular Biology

Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer

Suk Hyung Lee et al.

Article Cell & Tissue Engineering

Reconstruction of the Human Colon Epithelium In Vivo

Shinya Sugimoto et al.

CELL STEM CELL (2018)

Article Gastroenterology & Hepatology

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency

Jorik M. van Rijn et al.

GASTROENTEROLOGY (2018)

Article Multidisciplinary Sciences

Differentiated human airway organoids to assess infectivity of emerging influenza virus

Jie Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Multidisciplinary Sciences

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Patient derived organoids to model rare prostate cancer phenotypes

Loredana Puca et al.

NATURE COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche

Ysbrand M. Nusse et al.

NATURE (2018)

Article Multidisciplinary Sciences

Intra-tumour diversification in colorectal cancer at the single-cell level

Sophie F. Roerink et al.

NATURE (2018)

Article Cell Biology

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

Sandro Nuciforo et al.

CELL REPORTS (2018)

Article Biochemistry & Molecular Biology

Organoid Modeling of the Tumor Immune Microenvironment

James T. Neal et al.

Article Biochemistry & Molecular Biology

Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

Huili Hu et al.

Article Multidisciplinary Sciences

Transcriptome and epigenome landscape of human cortical development modeled in organoids

Anahita Amiri et al.

SCIENCE (2018)

Review Oncology

Organoids in cancer research

Jarno Drost et al.

NATURE REVIEWS CANCER (2018)

Article Gastroenterology & Hepatology

A High-Throughput Organoid Microinjection Platform to Study Gastrointestinal Microbiota and Luminal Physiology

Ian A. Williamson et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2018)

Article Gastroenterology & Hepatology

The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes

Yuta Kasagi et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2018)

Review Cell Biology

Organoids: A historical perspective of thinking in three dimensions

Marina Simian et al.

JOURNAL OF CELL BIOLOGY (2017)

Article Immunology

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

Daniel Ohlund et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Immunology

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

Yu Matsuzawa-Ishimoto et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Multidisciplinary Sciences

Visualization and targeting of LGR5+ human colon cancer stem cells

Mariko Shimokawa et al.

NATURE (2017)

Article Multidisciplinary Sciences

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

Claudia Y. Janda et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening

Laura Broutier et al.

NATURE MEDICINE (2017)

Article Biochemistry & Molecular Biology

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids

Fotios Sampaziotis et al.

NATURE MEDICINE (2017)

Article Multidisciplinary Sciences

Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner

Coyne G. Drummond et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells

Nesrin Tuysuz et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Emerging Biological Principles of Metastasis

Arthur W. Lambert et al.

Review Biochemistry & Molecular Biology

Modeling Development and Disease with Organoids

Hans Clevers

Article Medicine, Research & Experimental

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

Evelyn Fessler et al.

EMBO MOLECULAR MEDICINE (2016)

Article Biochemistry & Molecular Biology

R-spondin 1 and noggin facilitate expansion of resident stem cells from non-damaged gallbladders

Natalia Lugli et al.

EMBO REPORTS (2016)

Review Multidisciplinary Sciences

The coming of age of de novo protein design

Po-Ssu Huang et al.

NATURE (2016)

Article Multidisciplinary Sciences

Designer matrices for intestinal stem cell and organoid culture

Nikolce Glorevski et al.

NATURE (2016)

Article Cell Biology

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size

Lara Planas-Paz et al.

NATURE CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

Replication of human noroviruses in stem cell-derived human enteroids

Khalil Ettayebi et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

Thierry Jarde et al.

NATURE COMMUNICATIONS (2016)

Article Gastroenterology & Hepatology

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human stem Cell-Derived Colonoids

Julie In et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2016)

Review Cell Biology

Mini-Gut Organoids: Reconstitution of Stem Cell Niche

Shoichi Date et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 31 (2015)

Article Pharmacology & Pharmacy

Modeling rotavirus infection and antiviral therapy using primary intestinal organoids

Yuebang Yin et al.

ANTIVIRAL RESEARCH (2015)

Article Biochemistry & Molecular Biology

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch et al.

Article Biochemistry & Molecular Biology

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering et al.

Article Biochemistry & Molecular Biology

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj et al.

Article Gastroenterology & Hepatology

In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

Sina Bartfeld et al.

GASTROENTEROLOGY (2015)

Article Biochemical Research Methods

A 3-D enteroid-based model to study T-cell and epithelial cell interaction

Aneta Rogoz et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2015)

Article Multidisciplinary Sciences

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

Caroline A. Lindemans et al.

NATURE (2015)

Article Multidisciplinary Sciences

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids

Mami Matano et al.

NATURE MEDICINE (2015)

Article Biochemical Research Methods

Efficient genetic engineering of human intestinal organoids using electroporation

Masayuki Fujii et al.

NATURE PROTOCOLS (2015)

Article Multidisciplinary Sciences

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

Fleur Weeber et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

Dong Gao et al.

Article Biochemistry & Molecular Biology

Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

Wouter R. Karthaus et al.

Article Gastroenterology & Hepatology

Loss of Syntaxin 3 Causes Variant Microvillus Inclusion Disease

Caroline L. Wiegerinck et al.

GASTROENTEROLOGY (2014)

Article Medicine, Research & Experimental

TTC7A mutations disrupt intestinal epithelial apicobasal polarity

Amelie E. Bigorgne et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Biochemical Research Methods

Niche-independent high-purity cultures of Lgr5(+) intestinal stem cells and their progeny

Xiaolei Yin et al.

NATURE METHODS (2014)

Review Cell Biology

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

Eliah R. Shamir et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Multidisciplinary Sciences

Organogenesis in a dish: Modeling development and disease using organoid technologies

Madeline A. Lancaster et al.

SCIENCE (2014)

Article Biochemistry & Molecular Biology

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

Meritxell Huch et al.

EMBO JOURNAL (2013)

Article Multidisciplinary Sciences

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

Meritxell Huch et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

A functional CFTR assay using primary cystic fibrosis intestinal organoids

Johanna F. Dekkers et al.

NATURE MEDICINE (2013)

Review Cell Biology

Role of the extracellular matrix in regulating stem cell fate

Fiona M. Watt et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Review Gastroenterology & Hepatology

A nomenclature for intestinal in vitro cultures

Matthias Stelzner et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)

Article Multidisciplinary Sciences

Wnt/β-Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells

Katrin Hoffmeyer et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

Arnout G. Schepers et al.

EMBO JOURNAL (2011)

Article Gastroenterology & Hepatology

Duct Cells Contribute to Regeneration of Endocrine and Acinar Cells Following Pancreatic Damage in Adult Mice

Angela Criscimanna et al.

GASTROENTEROLOGY (2011)

Article Biochemistry & Molecular Biology

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

Akifumi Ootani et al.

NATURE MEDICINE (2009)