相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3
Florian Villegas et al.
CELL STEM CELL (2019)
Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine
Elyssa Bernfeld et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold
Rosalie E. Lawrence et al.
NATURE CELL BIOLOGY (2018)
Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms
Kuang Shen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis
Lu O. Sun et al.
CELL (2018)
Role of cell cycle regulators in adipose tissue and whole body energy homeostasis
I. C. Lopez-Mejia et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex
Ming-Yuan Su et al.
MOLECULAR CELL (2017)
Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling
Mariana E. G. de Araujo et al.
SCIENCE (2017)
Structural basis for the assembly of the Ragulator-Rag GTPase complex
Ryo Yonehara et al.
NATURE COMMUNICATIONS (2017)
p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway
Pauline Jeannot et al.
eLife (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2016)
Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival
Tania Campos et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
The non-canonical functions of p27(Kip1) in normal and tumor biology
Savitha S. Sharma et al.
CELL CYCLE (2016)
Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation
Francesca Nazio et al.
JOURNAL OF CELL BIOLOGY (2016)
A systems study reveals concurrent activation of AMPK and mTOR by amino acids
Piero Dalle Pezze et al.
NATURE COMMUNICATIONS (2016)
Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1
Wei Jia et al.
AUTOPHAGY (2015)
mTORC1 Phosphorylates UVRAG to Negatively Regulate Autophagosome and Endosome Maturation
Young-Mi Kim et al.
MOLECULAR CELL (2015)
Differential regulation of mTORC1 by leucine and glutamine
Jenna L. Jewell et al.
SCIENCE (2015)
MicroRNA-221 inhibits autophagy and promotes heart failure by modulating the p27/CDK2/mTOR axis
M. Su et al.
CELL DEATH AND DIFFERENTIATION (2015)
The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism
Chen-Song Zhang et al.
CELL METABOLISM (2014)
p27 Protein Protects Metabolically Stressed Cardiomyocytes from Apoptosis by Promoting Autophagy
Xuetao Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
Jing Zhou et al.
CELL RESEARCH (2013)
The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes
Taeko Soma-Nagae et al.
JOURNAL OF CELL SCIENCE (2013)
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival
Alejo Efeyan et al.
NATURE (2013)
Autophagy regulation and its role in cancer
Severine Lorin et al.
SEMINARS IN CANCER BIOLOGY (2013)
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
Jose A. Martina et al.
AUTOPHAGY (2012)
Cysteine cathepsins: From structure, function and regulation to new frontiers
Vito Turk et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2012)
Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels tomTORC1
Liron Bar-Peled et al.
CELL (2012)
p27Kip1 controls cytokinesis via the regulation of citron kinase activation
Murielle P. Serres et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Regulation of TFEB and V-ATPases by mTORC1
Samuel Pena-Llopis et al.
EMBO JOURNAL (2011)
p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
Eisuke Itakura et al.
JOURNAL OF CELL BIOLOGY (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro
M. P. Serres et al.
ONCOGENE (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
Oct1 is required for mTOR- induced G1 cell cycle arrest via the control of p27Kip1 expression
Mathieu Dalvai et al.
CELL CYCLE (2010)
Cycling through metabolism
Victor Aguilar et al.
EMBO MOLECULAR MEDICINE (2010)
Tumor suppressor p27Kip1 undergoes endolysosomal degradation through its interaction with sorting nexin 6
Jose J. Fuster et al.
FASEB JOURNAL (2010)
Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer
Guang Chen et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2010)
AMPK-Mediated Phosphorylation of Murine p27 at T197 Promotes Binding of 14-3-3 Proteins and Increases p27 Stability
John D. Short et al.
MOLECULAR CARCINOGENESIS (2010)
Termination of autophagy and reformation of lysosomes regulated by mTOR
Li Yu et al.
NATURE (2010)
PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation
Elsa-Noah N'Diaye et al.
EMBO REPORTS (2009)
A Novel Protein Associated with Membrane-type 1 Matrix Metalloproteinase Binds p27kip1 and Regulates RhoA Activation, Actin Remodeling, and Matrigel Invasion
Daisuke Hoshino et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy
Nao Hosokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
A Gene Network Regulating Lysosomal Biogenesis and Function
Marco Sardiello et al.
SCIENCE (2009)
AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27
John D. Short et al.
CANCER RESEARCH (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
CDK inhibitors: Cell cycle regulators and beyond
Arnaud Besson et al.
DEVELOPMENTAL CELL (2008)
mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation
Feng Hong et al.
MOLECULAR CELL (2008)
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim et al.
NATURE CELL BIOLOGY (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
Isabel M. Chu et al.
NATURE REVIEWS CANCER (2008)
Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype
Arnaud Besson et al.
GENES & DEVELOPMENT (2007)
Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size
Nao Hosokawa et al.
FEBS LETTERS (2007)
The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
Jiyong Liang et al.
NATURE CELL BIOLOGY (2007)
Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size
Nao Hosokawa et al.
FEBS LETTERS (2006)
A pathway in quiescent cells that controls p27(Kip1) stability, subcellular localization, and tumor suppression
A Besson et al.
GENES & DEVELOPMENT (2006)
Phosphorylation of mammalian target of rapamycin (mTOR) at ser-2448 is mediated by p70S6 kinase
GG Chiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
p27Kip1 modulates cell migration through the regulation of RhoA activation
A Besson et al.
GENES & DEVELOPMENT (2004)
Role for Rab7 in maturation of late autophagic vacuoles
S Jäger et al.
JOURNAL OF CELL SCIENCE (2004)
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
DD Sarbassov et al.
CURRENT BIOLOGY (2004)
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
H Harada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
分享论文
