Improving sensitivity of antimicrobial drug nitrofurazone detection in food and biological samples based on nanostructured anatase-titania sheathed reduced graphene oxide

In this study, we have prepared anatase titanium (IV) oxide warped reduced graphene oxide nanocomposites (TiO2-rGO NC) using ultrasonic methodology. The morphology of the TiO2-rGO NC was studied using FESEM and TEM. In addition, XRD, Raman, thermogravimetric analysis (TGA) and XPS are used to analyze the crystallinity and chemical composition of the TiO2-rGO NC. We have also investigated the electrochemical behavior of the as-prepared NCs with electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and different pulse voltammetry techniques (DPV). The TiO2-rGO NC modified electrode shows the lower charge transfer resistance (R-ct) of 62.87 omega. Next, the glassy carbon electrode (GCE) was modified with sonochemically prepared TiO2-rGO NC and used to determine the electrocatalytic reduction of nitrofurazone (NTF). Thus, the proposed sensor established the wider covering range (WCR) of 0.01 to 380 mu M and an excellent detection limit of 2.28 nM. Finally, the TiO2-rGO NC/GCE was applied to determine the NTF in real samples, including crayfish and human blood serum samples, which acquired good found and recovery values.