期刊
NANO RESEARCH
卷 14, 期 3, 页码 570-583出版社
TSINGHUA UNIV PRESS
DOI: 10.1007/s12274-020-3053-9
关键词
nanozymes; carbon nanomaterials; carbon nanozymes; enzyme-like activity
类别
资金
- China Postdoctoral Science Foundation [2019T120754, 2018M633229]
- Sanming Project of Medicine in Shenzhen [SZSM201612031]
- Natural Science Foundation of Guangdong Province of China [2018A030310665, 2018A0303130295]
- Shenzhen Science and Technology Innovation Committee [ZDSYS201707281114196, JCYJ20170306091657539, JCYJ20170413162242627, JCYJ20190806163814395, JCYJ-20170306091452714, GJHZ20170313172439851]
- Development and Reform Commission of Shenzhen Municipality [S2016005470013]
- National Key R&D Program of China [2017YFA0205501]
- National Natural Science Foundation of China [81722024, 81571728]
Nanozymes are nanomaterials with enzyme-like properties that address the limitations of traditional enzymes and offer multifunctional platforms for biomedical applications. Carbon nanomaterials, with well-defined structures, have shown to be ideal substitutes for traditional enzymes in mimicking the catalytic centers of natural enzymes.
Nanozymes are nanomaterials with enzyme-like properties that have attracted significant interest owing to their capability to address the limitations of traditional enzymes such as fragility, high cost, and impossible mass production. Over the past decade, a broad variety of nanomaterials have been found to mimic the enzyme-like activity by engineering the active centers of natural enzymes or developing multivalent elements within nanostructures. Carbon nanomaterials with well-defined electronic and geometric structures have served as favorable surrogates of traditional enzymes by mimicking the highly evolved catalytic center of natural enzymes. In particular, by combining the unique electronic, optical, thermal, and mechanical properties, carbon nanomaterials-based nanozymes can offer a variety of multifunctional platforms for biomedical applications. In this review, we will introduce the enzymatic characteristics and recent advances of carbon nanozymes, and summarize their significant applications in biomedicine.
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