相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。TIR domains of plant immune receptors are NAD+-cleaving enzymes that promote cell death
Li Wan et al.
SCIENCE (2019)
NAD+ cleavage activity by animal an plant TIR domains in cell death pathways
Shane Horsefield et al.
SCIENCE (2019)
Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2)
Buthaina Hussein et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Antimalarial Properties of Dunnione Derivatives as NQO2 Substrates
Monivan Chhour et al.
MOLECULES (2019)
Is There Sufficient Evidence that the Melatonin Binding Site MT3 Is Quinone Reductase 2?
Jean A. Boutin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2019)
S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization
Jean A. Boutin et al.
MOLECULAR PHARMACOLOGY (2019)
The mouse Gene Expression Database (GXD): 2019 update
Constance M. Smith et al.
NUCLEIC ACIDS RESEARCH (2019)
Resveratrol, human health and winemaking perspectives
Raul Francisco Pastor et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2019)
Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation
Edy Meiyanto et al.
ADVANCED PHARMACEUTICAL BULLETIN (2019)
Evaluation of analogues of furan-amidines as inhibitors of NQO2
Soraya Alnabulsi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Oxidative stress and neurodegeneration: The possible contribution of quinone reductase 2
Laure-Estelle Cassagnes et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
Vyacheslav Akimov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
NRH:quinone oxidoreductase 2 (NQO2) and glutaminase (GLS) both play a role in large extracellular vesicles (LEV ) formation in preclinical LNCaP-C4-2B prostate cancer mode of progressive metastasis
Thambi Dorai et al.
PROSTATE (2018)
UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
Vyacheslav Akimov et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
撤稿声明: Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors (Retraction of Vol 70, Pg 1006, 2010)
Jun Shen et al.
CANCER RESEARCH (2018)
Cyclic Changes in Active Site Polarization and Dynamics Drive the Ping-pong Kinetics in NRH:Quinone Oxidoreductase 2: An Insight from QM/MM Simulations
Clorice R. Reinhardt et al.
ACS CATALYSIS (2018)
Status of Artemisinin Resistance in Malaria Parasite Plasmodium falciparum from Molecular Analyses of the Kelch13 Gene in Southwestern Nigeria
Mary Aigbiremo Oboh et al.
BIOMED RESEARCH INTERNATIONAL (2018)
Prevalence of chloroquine resistance alleles among Plasmodium falciparum parasites in countries affected by malaria disease since change of treatment policy: a systematic review protocol
Moses Ocan et al.
SYSTEMATIC REVIEWS (2018)
The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2)
Zoe Riches et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2017)
Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives
Laure-Estelle Cassagnes et al.
MOLECULES (2017)
A subcellular map of the human proteome
Peter J. Thul et al.
SCIENCE (2017)
The target landscape of clinical kinase drugs
Susan Klaeger et al.
SCIENCE (2017)
NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development
Dandan Chen et al.
BIOLOGY OF REPRODUCTION (2017)
Quinone reductase 2 as a promising target of melatonin therapeutic actions
Jean A. Boutin
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
Non-symmetrical furan-amidines as novel leads for the treatment of cancer and malaria
Soraya Alnabulsi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection
Elzbieta Janda et al.
AUTOPHAGY (2015)
Binding of DNA-Intercalating Agents to Oxidized and Reduced Quinone Reductase 2
Kevin K. K. Leung et al.
BIOCHEMISTRY (2015)
Cytoprotective Effect of Afobazole and Its Main Metabolite M-11
I. A. Kadnikov et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2015)
In cellulo monitoring of quinone reductase activity and reactive oxygen species production during the redox cycling of 1,2 and 1,4 quinones
Laure-Estelle Cassagnes et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Melatonin: Physiological effects in humans
B. Claustrat et al.
NEUROCHIRURGIE (2015)
Tissue-based map of the human proteome
Mathias Uhlen et al.
SCIENCE (2015)
Quinone Reductase 2 Is an Adventitious Target of Protein Kinase CK2 Inhibitors TBBz (TBI) and DMAT
Kevin K. K. Leung et al.
BIOCHEMISTRY (2015)
From French Paradox to Cancer Treatment: Anti-cancer Activities and Mechanisms of Resveratrol
Xuan Yang et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2014)
NQO2 Is a Reactive Oxygen Species Generating Off-Target for Acetaminophen
Teemu P. Miettinen et al.
MOLECULAR PHARMACEUTICS (2014)
A draft map of the human proteome
Min-Sik Kim et al.
NATURE (2014)
Biochemical and Cellular Evidence Demonstrating AKT-1 as a Binding Partner for Resveratrol Targeting Protein NQO2
Tze-Chen Hsieh et al.
PLOS ONE (2014)
Effect of Afobazole on Activity of Quinone Reductase 2
I. A. Kadnikov et al.
PHARMACEUTICAL CHEMISTRY JOURNAL (2014)
Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2
Sarah E. St John et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
The antidote effect of quinone oxidoreductase 2 inhibitor against paraquat-induced toxicity in vitro and in vivo
Elzbieta Janda et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Chloroquine Binding Reveals Flavin Redox Switch Function of Quinone Reductase 2
Kevin K. K. Leung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Initial Quantitative Proteomic Map of 28 Mouse Tissues Using the SILAC Mouse
Tamar Geiger et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
Integrated proteomic analysis of post-translational modifications by serial enrichment
Philipp Mertins et al.
NATURE METHODS (2013)
Flavin adenine dinucleotide content of quinone reductase 2: Analysis and optimization for structure-function studies
Kevin Ka Ki Leung et al.
ANALYTICAL BIOCHEMISTRY (2012)
Synthesis of novel MT3 receptor ligands via an unusual Knoevenagel condensation
Maria S. Volkova et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Control of stability of cyclin D1 by quinone reductase 2 in CWR22Rv1 prostate cancer cells
Tze-chen Hsieh et al.
CARCINOGENESIS (2012)
Characterization of cofactors, substrates and inhibitor binding to flavoenzyme quinone reductase 2 by automated supramolecular nano-electrospray ionization mass spectrometry
Mathias Antoine et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2012)
Design, Synthesis, and Biological Evaluation of Potent Quinoline and Pyrroloquinoline Ammosamide Analogues as Inhibitors of Quinone Reductase 2
P. V. Narasimha Reddy et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Dabigatran and Dabigatran Ethyl Ester: Potent Inhibitors of Ribosyldihydronicotinamide Dehydrogenase (NQO2)
Simon Michaelis et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
In Silico Screening Reveals Structurally Diverse, Nanomolar Inhibitors of NQO2 That Are Functionally Active in Cells and Can Modulate NF-kappa B Signaling
Karen A. Nolan et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Screening Natural Products for Inhibitors of Quinone Reductase-2 Using Ultrafiltration LC-MS
Yongsoo Choi et al.
ANALYTICAL CHEMISTRY (2011)
Flavin Redox Switching of Protein Functions
Donald F. Becker et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition
Marine Dufour et al.
CHEMBIOCHEM (2011)
Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3
Veronique Leclerc et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Insights into the redox cycle of human quinone reductase 2
Karine Reybier et al.
FREE RADICAL RESEARCH (2011)
Novel Inhibitors of NRH:Quinone Oxidoreductase 2 (NQO2): Crystal Structures, Biochemical Activity, and Intracellular Effects of Imidazoacridin-6-ones
Mark S. Dunstan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
X-ray structural studies of quinone reductase 2 nanomolar range inhibitors
Scott D. Pegan et al.
PROTEIN SCIENCE (2011)
Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells
Takahito Nishiyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer
Bin Sun et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Triazoloacridin-6-ones as novel inhibitors of the quinone oxidoreductases NQO1 and NQO2
Karen A. Nolan et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2)
Karen A. Nolan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Imidazoacridin-6-ones as novel inhibitors of the quinone oxidoreductase NQO2
K. A. Nolan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
被撤回的出版物: Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors (Retracted article. See vol. 78, pg. 6345, 2018)
Jun Shen et al.
CANCER RESEARCH (2010)
Old and new inhibitors of quinone reductase 2
Gilles Ferry et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces Species, Strain CNS284
Martin Conda-Sheridan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Quaternary structure changes in a second Per-Arnt-Sim domain mediate intramolecular redox signal relay in the NifL regulatory protein
Peter Slavny et al.
MOLECULAR MICROBIOLOGY (2010)
Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway
Anastasia A. Khutornenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Biochemistry of Drug Metabolism - An Introduction Part 5. Metabolism and Bioactivity
Bernard Testa et al.
CHEMISTRY & BIODIVERSITY (2009)
The Biochemistry of Drug Metabolism - An Introduction
Stefanie D. Krämer et al.
CHEMISTRY & BIODIVERSITY (2009)
Functional polymorphisms, altered gene expression and genetic association link NRH:quinone oxidoreductase 2 to breast cancer with wild-type p53
Ke-Da Yu et al.
HUMAN MOLECULAR GENETICS (2009)
Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory Activities
Arup Maiti et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)
Jonathan A. Winger et al.
BMC STRUCTURAL BIOLOGY (2009)
Interactions of DB75, a novel antimalarial agent, with other antimalarial drugs in vitro
Anne E. Purfield et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2
Barbara Calamini et al.
BIOCHEMICAL JOURNAL (2008)
Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3
Mohamed Ettaoussi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
The Biochemistry of Drug Metabolism - An Introduction Part 4. Reactions of Conjugation and Their Enzymes
Bernard Testa et al.
CHEMISTRY & BIODIVERSITY (2008)
The Biochemistry of Drug Metabolism - An Introduction
Stefanie D. Krämer et al.
CHEMISTRY & BIODIVERSITY (2008)
Quinone reductase 2 is a catechol quinone reductase
Yue Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
SALMON:: Solvent accessibility, ligand binding, and mapping of ligand orientation by NMR Spectroscopy
Christian Ludwig et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
MT3/QR2 melatonin binding site does not use melatonin as a substrate or a co-substrate
Jean A. Boutin et al.
JOURNAL OF PINEAL RESEARCH (2008)
Association of NRH:quinone oxidoreductase 2 gene promoter polymorphism with higher gene expression and increased susceptibility to Parkinson's disease
Wei Wang et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor:: hypothesis and significance
Dun-Xian Tan et al.
JOURNAL OF PINEAL RESEARCH (2007)
NAD(P)H:quinone oxidoreductase1 and NRH:quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism
David Jamieson et al.
CLINICAL CANCER RESEARCH (2007)
The biochemistry of drug metabolism - An introduction Part 3. Reactions of hydrolysis and their enzymes
Bernard Testa et al.
CHEMISTRY & BIODIVERSITY (2007)
New ligands at the melatonin binding site MT3
MF Boussard et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2006)
The biochemistry of drug metabolism - An introduction - Part 1. Principles and overview
Bernard Testa et al.
CHEMISTRY & BIODIVERSITY (2006)
Characterization of the melatoninergic MT3 binding site on the NRH:quinone oxidoreductase 2 enzyme
F Mailliet et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Binding of the anticancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex
M AbuKhader et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954
Y Fu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Quinone reductase 2 substrate specificity and inhibition pharmacology
JA Boutin et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2005)
Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines
JJ Kwiek et al.
BIOCHEMISTRY (2004)
A gene atlas of the mouse and human protein-encoding transcriptomes
AI Su et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Crystal structure of quinone reductase 2 in complex with resveratrol
L Buryanovskyy et al.
BIOCHEMISTRY (2004)
Sp3 repression of polymorphic human NRH:Quinone oxidoreductase 2 gene promoter
W Wang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Post-translational modification of bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3
MD Esposti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Discovery of novel targets of quinoline drugs in the human purine binding proteome
PR Graves et al.
MOLECULAR PHARMACOLOGY (2002)
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity
DJ Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT3
V Leclerc et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
NRH:quinone oxidoreductase2 (NQO2)
DJ Long et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2000)
Identification of the melatonin-binding site MT3 as the quinone reductase 2
O Nosjean et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Structure-function studies of DT-diaphorase (NQO1) and NRH:quinone oxidoreductase (NQO2)
S Chen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
Structures of mammalian cytosolic quinone reductases
CE Foster et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)
Mouse NRH:quinone oxidoreductase (NQO2):: cloning of cDNA and gene- and tissue-specific expression
DJ Long et al.
GENE (2000)