期刊
MICROCHIMICA ACTA
卷 187, 期 11, 页码 -出版社
SPRINGER WIEN
DOI: 10.1007/s00604-020-04562-7
关键词
C-reactive protein; Field-effect transistor; Gold nanoparticles; Molybdenum disulfide
资金
- Fundamental Research Grant Scheme (FRGS) [FRGS/1/2017/STG05/UNIMAP/03/3]
- Ministry of Education Malaysia
Nanofabricated gold nanoparticles (Au-NPs) on MoS(2)nanosheets (Au-NPs/MoS2) in back-gated field-effect transistor (BG-FET) are presented, which acts as an efficient semiconductor device for detecting a low concentration of C-reactive protein (C-RP). The decorated nanomaterials lead to an enhanced electron conduction layer on a 100-mu m-sized transducing channel. The sensing surface was characterized by Raman spectroscopy, ultraviolet-visible spectroscopy (UV-Vis), atomic force microscopy (AFM), scanning electron microscopy (SEM), and high-power microscopy (HPM). The BG-FET device exhibits an excellent limit of detection of 8.38 fg/mL and a sensitivity of 176 nA/g center dot mL(-1). The current study with Au-NPs/MoS2 BG-FET displays a new potential biosensing technology; especially for integration into complementary metal oxide (CMOS) technology for hand-held future device application.
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