Advances in Exosomes-Based Drug Delivery Systems

Exosomes, a subgroup of extracellular vesicles, are important mediators of long-distance intercellular communication and are involved in a diverse range of biological processes such as the transport of lipids, proteins, and nucleic acids. Researchers, seeing the problems caused by the toxic effects and clearance of synthetic nanoparticles, consider exosomes as an interesting alternative to such nanoparticles in the specific and controlled transport of drugs. In recent years, there have been remarkable advances in the use of exosomes in cancer therapeutics or for treating neurological diseases, among other applications. The objective of this work is to analyze studies focused on exosomes used in drug delivery system, present and future applications in this field of research are discussed based on the results obtained.

Automated summary

Exosomes, a subgroup of extracellular vesicles, have been recognized as promising alternatives to synthetic nanoparticles for drug delivery due to their ability to transport various molecules and avoid toxic effects. Recent advancements have shown significant potential for the use of exosomes in cancer therapeutics and neurological disease treatments, among other applications, with further research needed to explore future directions and applications.