期刊
LARYNGOSCOPE
卷 131, 期 5, 页码 E1519-E1523出版社
WILEY
DOI: 10.1002/lary.29160
关键词
Kikuchi-Fujimoto disease; core needle biopsy; fine-needle aspiration cytology; cervical lymphadenopathy; subacute necrotizing lymphadenitis
The study aimed to evaluate the efficacy of US-CNB and compare it with US-FNAC in diagnosing KFD. US-CNB showed higher diagnostic accuracy compared to US-FNAC, indicating it as a safe and effective primary modality for the pathological diagnosis of KFD.
Objectives/Hypothesis Ultrasound-guided fine-needle aspiration cytology (US-FNAC) is a well-established procedure performed to establish the diagnosis of Kikuchi-Fujimoto disease (KFD). Ultrasound-guided core needle biopsy (US-CNB) is an alternative diagnostic tool for KFD. However, the efficacy of US-CNB is not well evaluated. This study aimed to evaluate the efficacy of US-CNB and compare it with that of US-FNAC in the diagnosis of KFD. Study Design Retrospective cohort study. Methods We analyzed 170 patients who were diagnosed with KFD between January 2009 and May 2019. US-FNAC, US-CNB, and excisional biopsy were performed in 47, 114, and 9 patients, respectively. Diagnostic accuracies of US-FNAC and US-CNB were analyzed and compared. Results Of the 170 patients, 45 and 125 were men and women, respectively. The mean age was 26.9 +/- 9.1 years. The most common symptom was cervical lymphadenopathy, followed by fever, headache, and myalgia. The diagnosis of KFD was established primarily by US-FNAC in 21 (44.7%) of the 47 patients, by US-CNB in 109 (95.6%) of the 114 patients, and by excisional biopsy in all 9 patients. There was no specific major complication related to US-FNAC and US-CNB. Conclusion US-CNB can be considered safe and effective and used as the primary modality for the pathological diagnosis of KFD. Level of Evidence 4.Laryngoscope, 2020
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