期刊
JOURNAL OF UROLOGY
卷 205, 期 2, 页码 595-602出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JU.0000000000001368
关键词
minimally invasive surgical procedures; robotics; complications; kidney transplantation
The study revealed that robotic-assisted kidney transplantation was associated with fewer postoperative complications and improved patient comfort compared to traditional open surgery, with comparable outcomes in terms of graft function, graft rejection, and overall survival between the two techniques.
Purpose: We report on comparative effectiveness of minimally invasive versus traditional open kidney transplantation. Materials and Methods: We undertook a prospective cohort study of 654 patients who underwent open or robotic kidney transplantation at a single tertiary care hospital between January 2013 and December 2015. Primary outcome was delayed graft function, defined as the need for dialysis within 1 week of surgery. Secondary outcomes included postoperative complications, pain, graft rejection, and graft and patient survival. Nonparsimonious propensity score and Ding-VanderWeele analytical methods were used to account for confounding bias. Results: Within the 1:3 matched cohort (robotic 126, open 378; well matched with standardized mean difference similar to 10%), the robotic approach was associated with lower rates of wound infections (0% vs 4%, p=0.023) and symptomatic lymphoceles (0% vs 7% at 36 months, p=0.003), as well as reduced postoperative pain, requirement for narcotic analgesia and blood loss. There were no differences between the 2 groups, robotic versus open, with respect to graft function (delayed graft function 0% vs 2.4%, p=0.081), hospital stay (median 8 days for both, p=0.647), graft rejection (16.2% vs 18.6% at 36 months, p=0.643), and graft (95.2% vs 96.3% at 36 months, p=0.266) and overall survival (94.5% vs 98.1% at 36 months, p=0.307). Ding-VanderWeele analysis suggested minimal influence of unknown confounders on study findings. Conclusions: Robotic kidney transplantation with regional hypothermia was associated with a lower rate of postoperative complications and improved patient comfort in comparison to open kidney transplantation. Graft function, and graft and overall survival were comparable between the 2 techniques.
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