Synthesis of novel organotin(IV) complex for multiple applications: as biologically potent and single molecular precursor

This work reports a facile solution-based synthesis of novel single molecular precursor (SMP), triphenylstannyl 4-((4-bromophenyl) amino)-4-oxobut-2-enoate complex (2). The as-prepared SMP was characterized by single crystal X-rays diffraction, elemental analysis,H-1 NMR,C-13 NMR and Mass spectrometry. The thermal properties of as-prepared SMP were assessed by thermogravimetric analysis and differential calorimetry. The as-prepared complex showed excellent DNA binding property in vivo experiments. The as-prepared complex (2) also revealed good antileishmanial and anticancer properties. Lastly, high-quality transparent SnO(2)thin films were obtained by aerosol-assisted chemical vapors deposition on common window glass. The morphological and structural studies of as-deposited thin films were performed by XRD and FE-SEM.

Automated summary

This work describes a facile solution-based synthesis of a novel single molecular precursor with excellent DNA binding and anti-leishmanial properties, as well as the deposition of high-quality SnO(2) thin films on common window glass.