相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Palmitic acid triggers inflammatory responses in N42 cultured hypothalamic cells partially via ceramide synthesis but not via TLR4
Domenico Sergi et al.
NUTRITIONAL NEUROSCIENCE (2020)
Lipid excess affects chaperone-mediated autophagy in hypothalamus
M. Portovedo et al.
BIOCHIMIE (2020)
Palmitic Acid Reduces the Autophagic Flux and Insulin Sensitivity Through the Activation of the Free Fatty Acid Receptor 1 (FFAR1) in the Hypothalamic Neuronal Cell Line N43/5
Maria Paz Hernandez-Caceres et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
Nerve Growth Factor modulates LPS - induced microglial glycolysis and inflammatory responses
Georgia Fodelianaki et al.
EXPERIMENTAL CELL RESEARCH (2019)
Lipotoxicity in Kidney, Heart, and Skeletal Muscle Dysfunction
Hiroshi Nishi et al.
NUTRIENTS (2019)
Palmitate-induced autophagy liberates monounsaturated fatty acids and increases Agrp expression in hypothalamic cells
Seokjae Park et al.
ANIMAL CELLS AND SYSTEMS (2019)
The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules
Miruna Nemecz et al.
FRONTIERS IN PHARMACOLOGY (2019)
The partial inhibition of hypothalamic IRX3 exacerbates obesity
Thiago Matos de Araujo et al.
EBIOMEDICINE (2019)
Is Palmitoleic Acid a Plausible Nonpharmacological Strategy to Prevent or Control Chronic Metabolic and Inflammatory Disorders?
Camila O. de Souza et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2018)
Palmitate induces neuroinflammation, ER stress, and Pomc mRNA expression in hypothalamic mHypoA-POMC/GFP neurons through novel mechanisms that are prevented by oleate
Erika K. Tse et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018)
Effects of saturated palmitic acid and omega-3 polyunsaturated fatty acids on Sertoli cell apoptosis
Xuechun Hu et al.
SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE (2018)
Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances beta-cell function of obese Zucker rats
Melanie Campana et al.
MOLECULAR METABOLISM (2018)
Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide
Anne Gulbins et al.
MOLECULAR PSYCHIATRY (2018)
Autophagy and Akt in the protective effect of erythropoietin helix B surface peptide against hepatic ischaemia/reperfusion injury in mice
Rumeng Tan et al.
SCIENTIFIC REPORTS (2018)
High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons
P. S. Dalvi et al.
INTERNATIONAL JOURNAL OF OBESITY (2017)
Hypothalamic Lipids: Key Regulators of Whole Body Energy Balance
Ismael Gonzalez-Garcia et al.
NEUROENDOCRINOLOGY (2017)
Suppression of Osteoclastogenesis by Melatonin: A Melatonin Receptor-Independent Action
Hyung Joon Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Multi-parametric imaging of cell heterogeneity in apoptosis analysis
Ivan A. Vorobjev et al.
METHODS (2017)
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Michiru Nishita et al.
SCIENTIFIC REPORTS (2017)
Deconstructing metabolic inflammation using cellular systems
Kenny L. Chan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2017)
Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression
Tae Seok Oh et al.
AUTOPHAGY (2016)
p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation
Wei Jing Liu et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2016)
Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment
Meric Erikci Ertunc et al.
JOURNAL OF LIPID RESEARCH (2016)
Autophagy proteins are modulated in the liver and hypothalamus of the offspring of mice with diet-induced obesity
Andressa Reginato et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2016)
Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation
Ismail Cimen et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Hypothalamic Inflammation in the Control of Metabolic Function
Martin Valdearcos et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 77 (2015)
Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK)
Kenny L. Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Ceramide metabolism regulates autophagy and apoptotic cell death induced by melatonin in liver cancer cells
Raquel Ordonez et al.
JOURNAL OF PINEAL RESEARCH (2015)
Applications of flow cytometry for measurement of autophagy
Alik Demishtein et al.
METHODS (2015)
Palmitic acid induces autophagy in hepatocytes via JNK2 activation
Qian-qian Tu et al.
ACTA PHARMACOLOGICA SINICA (2014)
Central Ceramide-Induced Hypothalamic Lipotoxicity and ER Stress Regulate Energy Balance
Cristina Contreras et al.
CELL REPORTS (2014)
p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer
Ioannis P. Nezis et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Guidelines for the use and interpretation of assays for monitoring autophagy
Daniel J. Klionsky et al.
AUTOPHAGY (2012)
Role of Hypothalamic Proopiomelanocortin Neuron Autophagy in the Control of Appetite and Leptin Response
Wenying Quan et al.
ENDOCRINOLOGY (2012)
Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)
Shi Hao Tan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Obesity is associated with hypothalamic injury in rodents and humans
Joshua P. Thaler et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Testosterone Plus Low-Intensity Physical Training in Late Life Improves Functional Performance, Skeletal Muscle Mitochondrial Biogenesis, and Mitochondrial Quality Control in Male Mice
Wen Guo et al.
PLOS ONE (2012)
Neuronal Autophagy: A Housekeeper or a Fighter in Neuronal Cell Survival?
Jin-A Lee
Experimental Neurobiology (2012)
Autophagy in the control of food intake
Rajat Singh
ADIPOCYTE (2012)
The Role of Atg Proteins in Autophagosome Formation
Noboru Mizushima et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance
Susmita Kaushik et al.
CELL METABOLISM (2011)
Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation
Fredrik Karpe et al.
DIABETES (2011)
Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway
Qingyuan Meng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Methods in Mammalian Autophagy Research
Noboru Mizushima et al.
CELL (2010)
S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
Saeid Ghavami et al.
CELL RESEARCH (2010)
mTOR regulation of autophagy
Chang Hwa Jung et al.
FEBS LETTERS (2010)
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
Kelly A. Posey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Ceramide-induced autophagy To junk or to protect cells?
Sophie Pattingre et al.
AUTOPHAGY (2009)
Nutrient-dependent regulation of autophagy through the target of rapamycin pathway
Yu-Yun Chang et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Protective Role of Autophagy in Palmitate-Induced INS-1 beta-Cell Death
Sung-E Choi et al.
ENDOCRINOLOGY (2009)
Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity
Marciane Milanski et al.
JOURNAL OF NEUROSCIENCE (2009)
Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
Chie Ebato et al.
CELL METABOLISM (2008)
Regulatory T cells and the induction of IL-17
A. Kitani et al.
MUCOSAL IMMUNOLOGY (2008)
Sphingolipids and cell death
Albert Morales et al.
APOPTOSIS (2007)
Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation
G Lavieu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
CT De Souza et al.
ENDOCRINOLOGY (2005)
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
TKT Lam et al.
NATURE MEDICINE (2005)
Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1
F Scarlatti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Generation of a phenotypic array of hypothalamic neuronal cell models to study complex neuroendocrine disorders
DD Belsham et al.
ENDOCRINOLOGY (2004)
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
JA Chavez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Fatty acid uptake and incorporation in brain -: Studies with the perfusion model
QR Smith et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2001)