相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A High-Throughput Screening Identifies MICU1 Targeting Compounds
Giulia Di Marco et al.
CELL REPORTS (2020)
Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex
Minrui Fan et al.
NATURE (2020)
Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
Chongyuan Wang et al.
ELIFE (2020)
Structural insights into the Ca2+-dependent gating of the human mitochondrial calcium uniporter
Yan Wang et al.
ELIFE (2020)
Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU
Melissa J. S. MacEwen et al.
LIFE SCIENCE ALLIANCE (2020)
MICU3 is a tissue-specific enhancer of mitochondrial calcium uptake
Maria Patron et al.
CELL DEATH AND DIFFERENTIATION (2019)
Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter
Randi J. Parks et al.
CARDIOVASCULAR RESEARCH (2019)
The MCU Inhibitor Ds16570511 has Off-Target Effects on Mitochondrial Membrane Potential
Riley Payne et al.
BIOPHYSICAL JOURNAL (2019)
Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve
Tariq R. Altamimi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2019)
Progress in understanding mitochondrial calcium uniporter complex-mediated calcium signalling: A potential target for cancer treatment
Chaochu Cui et al.
BRITISH JOURNAL OF PHARMACOLOGY (2019)
Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter
Yan Wang et al.
CELL (2019)
Mitochondrial calcium uniporter complex modulation in cancerogenesis
Saverio Marchia et al.
CELL CYCLE (2019)
The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down-regulation and mitochondrial dynamics alteration
Ziqing Yu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)
MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
Benjamin Gottschalk et al.
NATURE COMMUNICATIONS (2019)
Dysregulation of Mitochondrial Ca2+ Uptake and Sarcolemma Repair Underlie Muscle Weakness and Wasting in Patients and Mice Lacking MICU1
Valentina Debattisti et al.
CELL REPORTS (2019)
Calcium, mitochondria and cell metabolism: A functional triangle in bioenergetics
Alice Rossi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2019)
The conserved aspartate ring of MCU mediates MICU1 binding and regulation in the mitochondrial calcium uniporter complex
Charles B. Phillips et al.
ELIFE (2019)
A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
Joshua J. Woods et al.
ACS CENTRAL SCIENCE (2019)
miR-181c Activates Mitochondrial Calcium Uptake by Regulating MICU1 in the Heart
Hemanth N. Banavath et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)
MICU1 Interacts with the D-Ring of the MCU Pore to Control Its Ca2+ Flux and Sensitivity to Ru360
Melanie Paillard et al.
MOLECULAR CELL (2018)
Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium
Salah Sommakia et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
Rapid frequency-dependent changes in free mitochondrial calcium concentration in rat cardiac myocytes
Rob C. I. Wust et al.
JOURNAL OF PHYSIOLOGY-LONDON (2017)
Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening
Daniela M. Arduino et al.
MOLECULAR CELL (2017)
Ion and inhibitor binding of the double-ring ion selectivity filter of the mitochondrial calcium uniporter
Chan Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Proteolytic control of the mitochondrial calcium uniporter complex
Chen-Wei Tsai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
MICU1 protects againstmyocardial ischemia/reperfusion injury and its control by the importer receptor Tom70
Qiang Xue et al.
CELL DEATH & DISEASE (2017)
Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU
Melanie Paillard et al.
CELL REPORTS (2017)
Pathological consequences of MICU1 mutations on mitochondrial calcium signalling and bioenergetics
Gauri Bhosale et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2017)
DS16570511 is a small-molecule inhibitor of the mitochondrial calcium uniporter
Naohiro Kon et al.
CELL DEATH DISCOVERY (2017)
Expression of the mitochondrial calcium uniporter in cardiac myocytes improves impaired mitochondrial calcium handling and metabolism in simulated hyperglycemia
Julieta Diaz-Juarez et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)
Translocation of iron from lysosomes to mitochondria during acetaminophen-induced hepatocellular injury: Protection by starch-desferal and minocycline
Jiangting Hu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria
Tim Koenig et al.
MOLECULAR CELL (2016)
MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration
Anil Noronha Antony et al.
NATURE COMMUNICATIONS (2016)
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload
Julia C. Liu et al.
CELL REPORTS (2016)
Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex
Ming-Feng Tsai et al.
ELIFE (2016)
Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood
David Lewis-Smith et al.
NEUROLOGY-GENETICS (2016)
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart
Tyler P. Rasmussen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition
Timothy S. Luongo et al.
CELL REPORTS (2015)
The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart
Jennifer Q. Kwong et al.
CELL REPORTS (2015)
Unresolved questions from the analysis of mice lacking MCU expression
Elizabeth Murphy et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
The elusive importance of being a mitochondrial Ca2+ uniporter
Diana Pendin et al.
CELL CALCIUM (2014)
Proteomic Mapping of the Human Mitochondrial Intermembrane Space in Live Cells via Ratiometric APEX Tagging
Victoria Hung et al.
MOLECULAR CELL (2014)
MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity
Maria Patron et al.
MOLECULAR CELL (2014)
Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling
Clare V. Logan et al.
NATURE GENETICS (2014)
MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
Gyoergy Csordas et al.
CELL METABOLISM (2013)
The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
Anna Raffaello et al.
EMBO JOURNAL (2013)
Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling
Veronica Eisner et al.
JOURNAL OF CELL SCIENCE (2013)
The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
Xin Pan et al.
NATURE CELL BIOLOGY (2013)
MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
Molly Plovanich et al.
PLOS ONE (2013)
EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex
Yasemin Sancak et al.
SCIENCE (2013)
Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter
Justin Schwartz et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Calcium transport across the inner mitochondrial membrane: Molecular mechanisms and pharmacology
Gyoergy Csordas et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
Joshua M. Baughman et al.
NATURE (2011)
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
Diego De Stefani et al.
NATURE (2011)
Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells
Eva Maria Garcia-Martinez et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Minocycline Sensitizes Rodent and Human Liver Mitochondria to the Permeability Transition: Implications for Toxicity in Liver Transplantation
Roland Mansson et al.
HEPATOLOGY (2010)
Ca2+ Hot Spots on the Mitochondrial Surface Are Generated by Ca2+ Mobilization from Stores, but Not by Activation of Store-Operated Ca2+ Channels
Marta Giacomello et al.
MOLECULAR CELL (2010)
Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface
Gyoergy Csordas et al.
MOLECULAR CELL (2010)
MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
Fabiana Perocchi et al.
NATURE (2010)
Minocycline and neurodegenerative diseases
Hye-Sun Kim et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
SR/ER-mitochondrial local communication: Calcium and ROS
Gyoergy Csordas et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)
Mitochondrial calcium transport in the heart: Physiological and pathological roles
Elinor J. Griffiths
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro
Michael St. Pierre et al.
EXPERIMENTAL BRAIN RESEARCH (2009)
Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition
Tom P. Theruvath et al.
HEPATOLOGY (2008)
Mitochondrial calcium signalling and cell death:: Approaches for assessing the role of mitochondrial Ca2+ uptake in apoptosis
Gyorgy Hajnoczky et al.
CELL CALCIUM (2006)
Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes
Christoph Maack et al.
CIRCULATION RESEARCH (2006)
Ca2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC)
Gyorgy Bathori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The mitochondrial calcium uniporter is a highly selective ion channel
Y Kirichok et al.
NATURE (2004)
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
PS Brookes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria
E Rapizzi et al.
JOURNAL OF CELL BIOLOGY (2002)
Mitochondria, Ca2+ and neurodegenerative disease
C Krieger et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
A mitochondrial perspective on cell death
P Bernardi et al.
TRENDS IN BIOCHEMICAL SCIENCES (2001)
Mitochondrial calcium transients in adult rabbit cardiac myocytes:: Inhibition by ruthenium red and artifacts caused by lysosomal loading of Ca2+-indicating fluorophores
DR Trollinger et al.
BIOPHYSICAL JOURNAL (2000)
Mitochondrial calcium in heart cells:: Beat-to-beat oscillations or slow integration of cytosolic transients?
J Hüser et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2000)