相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover
Yuki Tanaka et al.
GUT (2021)
GS-0976 (Firsocostat): an investigational liver-directed acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH)
Naim Alkhouri et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)
Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes
Marica Meroni et al.
EBIOMEDICINE (2020)
Nonalcoholic Steatohepatitis Is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates
Zobair Younossi et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2019)
MBOAT7 is anchored to endomembranes by six transmembrane domains
Andrea Caddeo et al.
JOURNAL OF STRUCTURAL BIOLOGY (2019)
Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease
Robert N. Helsley et al.
ELIFE (2019)
Phospholipid subcellular localization and dynamics
Yanbo Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
GS-0976 Reduces Hepatic Steatosis and Fibrosis Markers in Patients With Nonalcoholic Fatty Liver Disease
Rohit Loomba et al.
GASTROENTEROLOGY (2018)
Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis
Nicole Ehrhardt et al.
HUMAN MOLECULAR GENETICS (2017)
Phosphoinositides, Major Actors in Membrane Trafficking and Lipid Signaling Pathways
Johan-Owen De Craene et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
ER phospholipid composition modulates lipogenesis during feeding and in obesity
Xin Rong et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
A case of hypocholesterolemia and steatosis in a carrier of a PCSK9 loss-of-function mutation and polymorphisms predisposing to nonalcoholic fatty Liver disease
Mathilde Di Filippo et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2017)
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Stefan Stender et al.
NATURE GENETICS (2017)
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation
Chai-Wan Kim et al.
CELL METABOLISM (2017)
I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders
M. -F. Xia et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2016)
Mutations in MBOAT7, Encoding Lysophosphatidylinositol Acyltransferase I, Lead to Intellectual Disability Accompanied by Epilepsy and Autistic Features
Anide Johansen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent
Rosellina Margherita Mancina et al.
GASTROENTEROLOGY (2016)
Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins
Eriks Smagris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Small Intestine but Not Liver Lysophosphatidylcholine Acyltransferase 3 (Lpcat3) Deficiency Has a Dominant Effect on Plasma Lipid Metabolism
Inamul Kabir et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans
Panu K. Luukkonen et al.
JOURNAL OF HEPATOLOGY (2016)
Association of MBOAT7 gene variant with plasma ALT levels in children: the PANIC study
Anna Viitasalo et al.
PEDIATRIC RESEARCH (2016)
Phosphoinositides: Key modulators of energy metabolism
Dave Bridges et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2015)
Genetic Variation in Transmembrane 6 Superfamily Member 2 and the Risk of Nonalcoholic Fatty Liver Disease and Histological Disease Severity
Silvia Sookoian et al.
HEPATOLOGY (2015)
Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion
Xin Rong et al.
ELIFE (2015)
Pnpla3I148M Knockin Mice Accumulate PNPLA3 on Lipid Droplets and Develop Hepatic Steatosis
Eriks Smagris et al.
HEPATOLOGY (2015)
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Julia Kozlitina et al.
NATURE GENETICS (2014)
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
Quentin M. Anstee et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)
Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP2 in the Mouse
Karen E. Anderson et al.
PLOS ONE (2013)
The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals
Young-Ah Moon et al.
CELL METABOLISM (2012)
LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice
Hyeon-Cheol Lee et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Population-based risk factors and resource utilization for HCC: US perspective
A. Sanyal et al.
CURRENT MEDICAL RESEARCH AND OPINION (2010)
The Association of Genetic Variability in Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) with Histological Severity of Nonalcoholic Fatty Liver Disease
Yaron Rotman et al.
HEPATOLOGY (2010)
Polyunsaturated Fatty Acids Selectively Suppress Sterol Regulatory Element-binding Protein-1 through Proteolytic Processing and Autoloop Regulatory Circuit
Yoshinori Takeuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Prevalence of non-alcoholic fatty liver disease and its association with cardiovascular disease in patients with type 1 diabetes
Giovanni Targher et al.
JOURNAL OF HEPATOLOGY (2010)
Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance
Arun Radhakrishnan et al.
CELL METABOLISM (2008)
Lysophospholipid Acyltransferases and Arachidonate Recycling in Human Neutrophils
Miguel A. Gijon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
Stefano Romeo et al.
NATURE GENETICS (2008)
Mice lacking phosphatidylinositol transfer protein-α exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemia
JG Alb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation
M Matsuda et al.
GENES & DEVELOPMENT (2001)
分享论文
