期刊
JOURNAL OF INVESTIGATIVE DERMATOLOGY
卷 141, 期 2, 页码 274-284出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jid.2020.07.006
关键词
-
类别
资金
- U.S. National Institutes of Health [R01AR073665, R01AR069502, R13AR009431-55]
Atopic dermatitis is a common chronic inflammatory skin condition characterized by recurrent and pruritic skin eruptions. Multiple factors contribute to its pathogenesis, including skin barrier dysfunction, microbial dysbiosis, and immune dysregulation. Interactions among these factors form a complex multidirectional network that can exacerbate atopic skin disease but can also be ameliorated by targeted therapies.
Atopic dermatitis (AD) is a common, chronic, inflammatory skin condition characterized by recurrent and pruritic skin eruptions. Multiple factors contribute to the pathogenesis of AD, including skin barrier dysfunction, microbial dysbiosis, and immune dysregulation. Interactions among these factors form a complex, multidirectional network that can reinforce atopic skin disease but can also be ameliorated by targeted therapies. This review summarizes the complex interactions among contributing factors in AD and the implications on disease development and therapeutic interventions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据