期刊
JOURNAL OF INFECTIOUS DISEASES
卷 223, 期 1, 页码 15-18出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiaa632
关键词
SARS-CoV-2; viral shedding; nasopharynx; COVID-19
资金
- Swedish State Support for Clinical Research [ALFGBG-717531]
- SciLifeLab/KAW National COVID-19 Research Program Project [V-2020-0250]
The study found that viral RNA loads were highest early after symptom onset, and there was a moderate correlation between duration of symptoms and viral RNA shedding in patients with mild COVID-19.
This study reports longitudinal viral RNA loads from the nasopharynx/throat in patients with mild and severe/critical coronavirus disease 2019 (COVID-19). We also investigated whether the duration of symptoms correlated with the duration of viral RNA shedding. A total of 56 patients were included. The highest viral loads occurred early after onset of symptoms. Neither the viral RNA loads in the upper respiratory tract nor the time to viral RNA clearance differed between patients with mild or severe/critical disease. There was a moderate correlation between number of days with symptoms and number of days with viral RNA shedding in patients with mild COVID-19.
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