期刊
JOURNAL OF ATTENTION DISORDERS
卷 26, 期 1, 页码 34-47出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1087054720959712
关键词
fMRI; ADHD; multilayer community detection; dynamic network reconfiguration
资金
- National Natural Science Foundation of China [61873178, 61876124, 61906130]
- Key Research and Development Plan of Shanxi Province (International Scientific and Technical Cooperation) [201803D421047]
- National Key Research and Development Project [2018AAA0102604]
- Youth Fund Project of Shanxi Province [201901D211075]
This study found abnormalities in the dynamic community structure of ADHD patients. Compared to healthy controls, ADHD patients showed higher levels of flexibility and cohesion, with specific regional changes in the frontal lobe. These findings provide a new perspective on the understanding of dynamic organizational principles of communities in ADHD.
Objective: Some static network studies have suggested that the community structure in the brains of ADHD patients is altered. However, ADHD is now increasingly regarded as a disorder of neural dynamics, but the dynamic reconstruction of brain communities in ADHD patients is far from being understood. Method: Forty-two ADHD patients and fifty healthy controls participated in this study. We constructed a multilayer network model and calculated several metrics for quantifying community reconstruction at different levels. Results: Regardless of the level of research, the flexibility and cohesion of the ADHD patients were significantly higher than those of controls. In addition, the frontal lobe of ADHD patients presented a phenomenon of increasing peripheral areas and decreasing core areas. Conclusion: Our results indicate that ADHD patients do have abnormalities in dynamic community structure. These evidences provide a new perspective that advances the present understanding of the dynamic organizational principles of communities in ADHD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据