相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Oncolytic virotherapy: Challenges and solutions
Nasser Hashemi Goradel et al.
CURRENT PROBLEMS IN CANCER (2021)
Meningeal lymphatic vessels regulate brain tumor drainage and immunity
Xueting Hu et al.
CELL RESEARCH (2020)
VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours
Eric Song et al.
NATURE (2020)
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
Sangeeta Goswami et al.
NATURE MEDICINE (2020)
CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
Joseph A. Flores-Toro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
The BiTE (Bispecific T-Cell engager) platform: development and future potential of a targeted immuno-oncology therapy across Tumor Types
Hermann Einsele et al.
CANCER (2020)
Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
Jasneet Kaur Khalsa et al.
NATURE COMMUNICATIONS (2020)
Downregulation of the CCL2/CCR2 and CXCL10/CXCR3 axes contributes to antitumor effects in a mouse model of malignant glioma
Kenji Shono et al.
SCIENTIFIC REPORTS (2020)
Inflammatory microenvironment remodelling by tumour cells after radiotherapy
Martin McLaughlin et al.
NATURE REVIEWS CANCER (2020)
Brain immunology and immunotherapy in brain tumours
John H. Sampson et al.
NATURE REVIEWS CANCER (2020)
The blood-brain barrier and blood-tumour barrier in brain tumours and metastases
Costas D. Arvanitis et al.
NATURE REVIEWS CANCER (2020)
Astrocytes, the rising stars of the glioblastoma microenvironment
Mayra Brandao et al.
GLIA (2019)
Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma
Ae Kyung Park et al.
NEURO-ONCOLOGY (2019)
Molecular responses to immune checkpoint blockade in glioblastoma
Hirotaka Ito et al.
NATURE MEDICINE (2019)
CSF-1 controls cerebellar microglia and is required for motor function and social interaction
Veronika Kana et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid
Ji Hoon Ahn et al.
NATURE (2019)
Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance
Stacie K. Totsch et al.
ONCOGENE (2019)
Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma
Dieter Henrik Heiland et al.
NATURE COMMUNICATIONS (2019)
Experimental models and tools to tackle glioblastoma
Faye L. Robertson et al.
DISEASE MODELS & MECHANISMS (2019)
Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Mariangela Di Tacchio et al.
CANCER IMMUNOLOGY RESEARCH (2019)
Bispecific T-cell engagers: Towards understanding variables influencing the in vitro potency and tumor selectivity and their modulation to enhance their efficacy and safety
Diego Ellerman
METHODS (2019)
The role of CMV in glioblastoma and implications for immunotherapeutic strategies
Maryam Rahman et al.
ONCOIMMUNOLOGY (2019)
Expansion of effector and memory T cells is associated with increased survival in recurrent glioblastomas treated with dendritic cell immunotherapy
Marica Eoli et al.
NEURO-ONCOLOGY ADVANCES (2019)
Tumour-associated microglia/macrophages predict poor prognosis in high-grade gliomas and correlate with an aggressive tumour subtype
M. D. Sorensen et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2018)
Recombinant Poliovirus for Cancer Immunotherapy
Matthias Gromeier et al.
ANNUAL REVIEW OF MEDICINE, VOL 69 (2018)
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment (vol 32, pg 42, 2017)
Qianghu Wang et al.
CANCER CELL (2018)
T-cell Dysfunction in Glioblastoma: Applying a New Framework
Karolina I. Woroniecka et al.
CLINICAL CANCER RESEARCH (2018)
Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma
Frederick F. Lang et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
Blood-brain barrier (BBB) and the complement landscape
Jessy J. Alexander
MOLECULAR IMMUNOLOGY (2018)
Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma
Christine E. Brown et al.
MOLECULAR THERAPY (2018)
Current state of immunotherapy for glioblastoma
Michael Lim et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2018)
Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment
Wouter B. L. van den Bossche et al.
NEURO-ONCOLOGY (2018)
CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges
Stephen J. Bagley et al.
NEURO-ONCOLOGY (2018)
Recurrent Glioblastoma Treated with Recombinant Poliovirus
Annick Desjardins et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
CAR T cell immunotherapy for human cancer
Carl H. June et al.
SCIENCE (2018)
CARs versus BiTEs: A Comparison between T Cell-Redirection Strategies for Cancer Treatment
Clare Y. Slaney et al.
CANCER DISCOVERY (2018)
Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma
Tomas Garzon-Muvdi et al.
Oncotarget (2018)
Immune Microenvironment in Glioblastoma Subtypes
Zhihong Chen et al.
FRONTIERS IN IMMUNOLOGY (2018)
Macrophages of distinct origins contribute to tumor development in the lung
Pierre-Louis Loyher et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors
Pakawat Chongsathidkiet et al.
NATURE MEDICINE (2018)
Difference in immunosuppressive Cells Between Peritumoral Area and Tumor Core in Glioblastoma
Ryota Tamura et al.
WORLD NEUROSURGERY (2018)
Immune checkpoint inhibitors: recent progress and potential biomarkers
Pramod Darvin et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas
C. J. Herting et al.
GLIA (2017)
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
Yu Zhu et al.
IMMUNITY (2017)
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Susanne Krasemann et al.
IMMUNITY (2017)
Chemotherapy-induced immunomodulation in non-small-cell lung cancer: a rationale for combination chemoimmunotherapy
Hua Zheng et al.
IMMUNOTHERAPY (2017)
Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas
D. Yan et al.
ONCOGENE (2017)
Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice
Qiaoli Ma et al.
NATURE COMMUNICATIONS (2017)
Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
Spyros Darmanis et al.
CELL REPORTS (2017)
Oncolytic Viruses in Cancer Treatment A Review
Sean E. Lawler et al.
JAMA ONCOLOGY (2017)
Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy
Michael A. Cannarile et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment
Soren Muller et al.
GENOME BIOLOGY (2017)
Glioblastoma targeted therapy: updated approaches from recent biological insights
M. Touat et al.
ANNALS OF ONCOLOGY (2017)
Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination
Kristen A. Batich et al.
CLINICAL CANCER RESEARCH (2017)
The Microenvironmental Landscape of Brain Tumors
Daniela F. Quail et al.
CANCER CELL (2017)
Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study
Nicholas Butowski et al.
NEURO-ONCOLOGY (2016)
Astrocytes promote glioma invasion via the gap junction protein connexin43
W. C. Sin et al.
ONCOGENE (2016)
Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
David A. Reardon et al.
CANCER IMMUNOLOGY RESEARCH (2016)
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
David N. Louis et al.
ACTA NEUROPATHOLOGICA (2016)
The Lymphatic System in Disease Processes and Cancer Progression
Timothy P. Padera et al.
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 18 (2016)
A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Christopher G. Hubert et al.
CANCER RESEARCH (2016)
Molecular Pathways: Isocitrate Dehydrogenase Mutations in Cancer
Owen Clark et al.
CLINICAL CANCER RESEARCH (2016)
Expansion and Activation of CD103+ Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition
Helene Salmon et al.
IMMUNITY (2016)
Sall1 is a transcriptional regulator defining microglia identity and function
Anne Buttgereit et al.
NATURE IMMUNOLOGY (2016)
The role of microglia and macrophages in glioma maintenance and progression
Dolores Hambardzumyan et al.
NATURE NEUROSCIENCE (2016)
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
Ye Zhang et al.
NEURON (2016)
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
Daniela F. Quail et al.
SCIENCE (2016)
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
Robert L. Bowman et al.
CELL REPORTS (2016)
Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma
Nicole R. Parker et al.
SCIENTIFIC REPORTS (2016)
Glioblastoma: pathology, molecular mechanisms and markers
Kenneth Aldape et al.
ACTA NEUROPATHOLOGICA (2015)
The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma
Kathleen M. Mahoney et al.
CLINICAL THERAPEUTICS (2015)
A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
Aleksanteri Aspelund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Brain tumour cells interconnect to a functional and resistant network
Matthias Osswald et al.
NATURE (2015)
Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
Duane A. Mitchell et al.
NATURE (2015)
Structural and functional features of central nervous system lymphatic vessels
Antoine Louveau et al.
NATURE (2015)
Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1
Frank Szulzewsky et al.
PLOS ONE (2015)
The Blood-Brain Barrier
Richard Daneman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
Carola H. Ries et al.
CANCER CELL (2014)
EGFRvIII mCAR-Modified T-Cell Therapy Cures Mice with Established Intracerebral Glioma and Generates Host Immunity against Tumor-Antigen Loss
John H. Sampson et al.
CLINICAL CANCER RESEARCH (2014)
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
Ye Zhang et al.
JOURNAL OF NEUROSCIENCE (2014)
Immunocompetent murine models for the study of glioblastoma immunotherapy
Taemin Oh et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2014)
Molecular Subtypes of Glioblastoma Are Relevant to Lower Grade Glioma
Xiaowei Guan et al.
PLOS ONE (2014)
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Anoop P. Patel et al.
SCIENCE (2014)
Recruited Brain Tumor-Derived Mesenchymal Stem Cells Contribute to Brain Tumor Progression
Jinan Behnan et al.
STEM CELLS (2014)
Immune privilege of the CNS is not the consequence of limited antigen sampling
Melissa G. Harris et al.
SCIENTIFIC REPORTS (2014)
Assessment of blood-brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review
Anna K. Heye et al.
NEUROIMAGE-CLINICAL (2014)
Vasoactive intestinal peptide: a neuropeptide with pleiotropic immune functions
Mario Delgado et al.
AMINO ACIDS (2013)
The Definition of Primary and Secondary Glioblastoma
Hiroko Ohgaki et al.
CLINICAL CANCER RESEARCH (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
Correction: The Brain Microvascular Endothelium Supports T Cell Proliferation and Has Potential for Alloantigen Presentation
Julie Wheway et al.
PLoS One (2013)
An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma
Patrick C. Gedeon et al.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2013)
Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells
Jian Chen et al.
CELL (2012)
Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia
Melanie Greter et al.
IMMUNITY (2012)
Going Against the Tide - How Encephalitogenic T Cells Breach the Blood-Brain Barrier
Ruth Lyck et al.
JOURNAL OF VASCULAR RESEARCH (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
The anatomical and cellular basis of immune surveillance in the central nervous system
Richard M. Ransohoff et al.
NATURE REVIEWS IMMUNOLOGY (2012)
Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain
Lionel M. L. Chow et al.
CANCER CELL (2011)
Genetic Modeling of Gliomas in Mice: New Tools to Tackle Old Problems
Dolores Hambardzumyan et al.
GLIA (2011)
Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis
Camille L. Pittet et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Combined Flt3L/TK Gene Therapy Induces Immunological Surveillance Which Mediates an Immune Response Against a Surrogate Brain Tumor Neoantigen
Gwendalyn D. King et al.
MOLECULAR THERAPY (2011)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors
Nabil Ahmed et al.
CLINICAL CANCER RESEARCH (2010)
The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells
Richard Daneman et al.
PLOS ONE (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
IDH1 Mutations as Molecular Signature and Predictive Factor of Secondary Glioblastomas
Sumihito Nobusawa et al.
CLINICAL CANCER RESEARCH (2009)
Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
Marloes van Zwam et al.
JOURNAL OF PATHOLOGY (2009)
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
Roger Stupp et al.
LANCET ONCOLOGY (2009)
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis
Haihao Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Modeling Adult Gliomas Using RCAS/t-va Technology
Dolores Hambardzumyan et al.
TRANSLATIONAL ONCOLOGY (2009)
Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity
Kai Hildner et al.
SCIENCE (2008)
IDO expression in the brain: a double-edged sword
Erik Kwidzinski et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
What is the blood-brain barrier (not)?
Ingo Bechmann et al.
TRENDS IN IMMUNOLOGY (2007)
History of oncolytic viruses: Genesis to genetic engineering
Elizabeth Kelly et al.
MOLECULAR THERAPY (2007)
Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4(+) T cell compartment without affecting regulatory T-cell function
Peter E. Fecci et al.
CLINICAL CANCER RESEARCH (2007)
Dendritic cells pulsed with glioma lysates induce immunity against syngeneic intracranial gliomas and increase survival of tumor-bearing mice
S. Pellegatta et al.
NEUROLOGICAL RESEARCH (2006)
Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy
Tunde Szatmari et al.
CANCER SCIENCE (2006)
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Jeongwu Lee et al.
CANCER CELL (2006)
Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
PE Fecci et al.
CANCER RESEARCH (2006)
Integration of the subarachnoid space and lymphatics: Is it time to embrace a new concept of cerebrospinal fluid absorption?
Lena Koh et al.
FLUIDS AND BARRIERS OF THE CNS (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells
KS Kahlon et al.
CANCER RESEARCH (2004)
The blood-brain barrier and its role in immune privilege in the central nervous system
JS Pachter et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis
MM Mazanet et al.
JOURNAL OF IMMUNOLOGY (2002)
Basic principles of immunological surveillance of the normal central nervous system
WF Hickey
GLIA (2001)
Expression and function of the costimulatory molecules B7-1 (CD80) and B7-2 (CD86) in an in vitro model of the human blood-brain barrier
KIM Omari et al.
JOURNAL OF NEUROIMMUNOLOGY (2001)
Bone marrow-derived dendritic cells pulsed with tumor homogenate induce immunity against syngeneic intracerebral glioma
AB Heimberger et al.
JOURNAL OF NEUROIMMUNOLOGY (2000)