4.7 Review

Fused in Sarcoma (FUS) in DNA Repair: Tango with Poly(ADP-ribose) Polymerase 1 and Compartmentalisation of Damaged DNA

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Progress and outlook in studying the substrate specificities of PARPs and related enzymes

Marcin J. Suskiewicz et al.

Summary: Despite years of research on ADP-ribosyltransferases from the PARP family, their substrate specificity has remained unclear. Recent breakthroughs include identifying protein serine residues, cysteine, and tyrosine as potential targets of specific PARPs. These findings shed new light on PARP-mediated catalysis and caution to expect the unexpected with potential substrates.

FEBS JOURNAL (2021)

Article Biochemistry & Molecular Biology

Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS Mutations

Amirhossein Ghanbari Niaki et al.

MOLECULAR CELL (2020)

Review Clinical Neurology

Invited Review: The role of prion-like mechanisms in neurodegenerative diseases

Z. Jaunmuktane et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2020)

Article Multidisciplinary Sciences

Intrinsically disordered protein RBM14 plays a role in generation of RNA:DNA hybrids at double-strand break sites

Yumi Jang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Cell Biology

Poly(ADP-ribose): A Dynamic Trigger for Biomolecular Condensate Formation

Anthony K. L. Leung

TRENDS IN CELL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior

Titus M. Franzmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

The molecular language of membraneless organelles

Edward Gomes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Review Biochemistry & Molecular Biology

Cellular sensing by phase separation: Using the process, not just the products

Haneul Yoo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins

Elizaveta E. Alemasova et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Biochemistry & Molecular Biology

Eukaryotic Base Excision Repair: New Approaches Shine Light on Mechanism

William A. Beard et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 88 (2019)

Article Biochemistry & Molecular Biology

Molecular interactions underlying liquid-liquid phase separation of the FUS low-complexity domain

Anastasia C. Murthy et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)

Review Genetics & Heredity

Poly(ADP-Ribosylation) in Age-Related Neurological Disease

Leeanne McGurk et al.

TRENDS IN GENETICS (2019)

Review Cell Biology

The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers

Tatiana Kamaletdinova et al.

Review Biochemistry & Molecular Biology

Evidence for and against Liquid-Liquid Phase Separation in the Nucleus

Peng A et al.

NON-CODING RNA (2019)

Review Biochemical Research Methods

Intrinsically Disordered Proteome of Human Membrane-Less Organelles

April L. Darling et al.

PROTEOMICS (2018)

Review Biophysics

Formation of Chromatin Subcompartments by Phase Separation

Fabian Erdel et al.

BIOPHYSICAL JOURNAL (2018)

Review Cell Biology

Protein Phase Separation: A New Phase in Cell Biology

Steven Boeynaems et al.

TRENDS IN CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

Yuan Lin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Biochemistry & Molecular Biology

DNA-Damage Response RNA-Binding Proteins (DDRBPs): Perspectives from a New Class of Proteins and Their RNA Targets

Martin Dutertre et al.

JOURNAL OF MOLECULAR BIOLOGY (2017)

Article Biochemistry & Molecular Biology

The role of poly ADP-ribosylation in the first wave of DNA damage response

Chao Liu et al.

NUCLEIC ACIDS RESEARCH (2017)

Review Cell Biology

Expanding functions of ADP-ribosylation in the maintenance of genome integrity

K. Martin-Hernandez et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)

Review Biochemistry & Molecular Biology

Endogenous DNA Damage as a Source of Genomic Instability in Cancer

Anthony Tubbs et al.

Article Biochemistry & Molecular Biology

Readers of poly(ADP-ribose): designed to be fit for purpose

Federico Teloni et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Biochemistry & Molecular Biology

The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

M. Madan Babu

BIOCHEMICAL SOCIETY TRANSACTIONS (2016)

Article Neurosciences

Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis

Yulei Shang et al.

BRAIN RESEARCH (2016)

Review Biochemistry & Molecular Biology

Functional Role of ADP-Ribosyl-Acceptor Hydrolase 3 in poly(ADP-Ribose) Polymerase-1 Response to Oxidative Stress

Masato Mashimo et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2016)

Review Biochemistry & Molecular Biology

Roles of RNA-Binding Proteins in DNA Damage Response

Mihoko Kai

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Biochemistry & Molecular Biology

Poly(ADP-Ribose) polymerase 1 as a key regulator of DNA repair

S. N. Khodyreva et al.

MOLECULAR BIOLOGY (2016)

Review Neurosciences

TDP-43/FUS in motor neuron disease: Complexity and challenges

Erika N. Guerrero et al.

PROGRESS IN NEUROBIOLOGY (2016)

Review Cell Biology

Repair Pathway Choices and Consequences at the Double-Strand Break

Raphael Ceccaldi et al.

TRENDS IN CELL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation

Xin Sun et al.

PLOS BIOLOGY (2016)

Article Biochemistry & Molecular Biology

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

Avinash Patel et al.

Article Biochemistry & Molecular Biology

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

Yuan Lin et al.

MOLECULAR CELL (2015)

Article Biochemistry & Molecular Biology

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

Kathleen A. Burke et al.

MOLECULAR CELL (2015)

Article Multidisciplinary Sciences

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

Matthias Altmeyer et al.

NATURE COMMUNICATIONS (2015)

Review Genetics & Heredity

DNA repair mechanisms in cancer development and therapy

Alessandro Torgovnick et al.

FRONTIERS IN GENETICS (2015)

Review Neurosciences

Functions of FUS/TLS From DNA Repair to Stress Response: Implications for ALS

Reddy Ranjith Kumar Sama et al.

ASN NEURO (2014)

Article Cell Biology

Nuclear bodies: new insights into assembly/dynamics and disease relevance

Judith E. Sleeman et al.

CURRENT OPINION IN CELL BIOLOGY (2014)

Article Genetics & Heredity

Protein ADP-ribosylation and the cellular response to DNA strand breaks

K. W. Caldecott

DNA REPAIR (2014)

Article Biochemistry & Molecular Biology

Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms

Tatyana A. Shelkovnikova et al.

HUMAN MOLECULAR GENETICS (2014)

Editorial Material Cell Biology

Poly(ADP-ribose): An organizer of cellular architecture

Anthony K. L. Leung

JOURNAL OF CELL BIOLOGY (2014)

Article Neurosciences

FUS is Phosphorylated by DNA-PK and Accumulates in the Cytoplasm after DNA Damage

Qiudong Deng et al.

JOURNAL OF NEUROSCIENCE (2014)

Article Multidisciplinary Sciences

Self-assembled FUS binds active chromatin and regulates gene transcription

Liuqing Yang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Biochemistry & Molecular Biology

DNA damage: RNA-binding proteins protect from near and far

Martin Dutertre et al.

TRENDS IN BIOCHEMICAL SCIENCES (2014)

Review Genetics & Heredity

Is homologous recombination really an error-free process?

Jose Guirouilh-Barbat et al.

FRONTIERS IN GENETICS (2014)

Article Biochemistry & Molecular Biology

Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS

Kentaro Takahama et al.

CHEMISTRY & BIOLOGY (2013)

Article Biochemistry & Molecular Biology

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules

Caroline Vance et al.

HUMAN MOLECULAR GENETICS (2013)

Article Biochemistry & Molecular Biology

The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage

Adam S. Mastrocola et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Cell Biology

FUS/TLS Assembles Into Stress Granules and Is a Prosurvival Factor During Hyperosmolar Stress

Reddy Ranjith K. Sama et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2013)

Article Neurosciences

Fused in sarcoma (FUS): An oncogene goes awry in neurodegeneration

Dorothee Dormann et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2013)

Article Biochemistry & Molecular Biology

Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses

Stephanie Jungmichel et al.

MOLECULAR CELL (2013)

Article Neurosciences

Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

Desiree M. Baron et al.

MOLECULAR NEURODEGENERATION (2013)

Article Neurosciences

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons

Wen-Yuan Wang et al.

NATURE NEUROSCIENCE (2013)

Article Neurosciences

SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons

Matthew M. Dobbin et al.

NATURE NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

The Role of hnRPUL1 Involved in DNA Damage Response Is Related to PARP1

Zehui Hong et al.

PLOS ONE (2013)

Article Cell Biology

DNA Damage Response: Three Levels of DNA Repair Regulation

Bianca M. Sirbu et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)

Eva Bentmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Phase transitions in the assembly of multivalent signalling proteins

Pilong Li et al.

NATURE (2012)

Article Cell Biology

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA

Tomohiro Yamazaki et al.

CELL REPORTS (2012)

Article Clinical Neurology

Nuclear Transport Impairment of Amyotrophic Lateral Sclerosis-Linked Mutations in FUS/TLS

Daisuke Ito et al.

ANNALS OF NEUROLOGY (2011)

Article Geriatrics & Gerontology

Nuclear localization sequence of FUS and induction of stress granules by ALS mutants

Jozsef Gal et al.

NEUROBIOLOGY OF AGING (2011)

Article Biochemistry & Molecular Biology

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

Dorothee Dormann et al.

EMBO JOURNAL (2010)

Article Biochemistry & Molecular Biology

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

Daryl A. Bosco et al.

HUMAN MOLECULAR GENETICS (2010)

Article Biochemistry & Molecular Biology

Fused in sarcoma/translocated in liposarcoma: A multifunctional DNA/RNA binding protein

Shu Yang et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

The DNA Damage Response: Making It Safe to Play with Knives

Alberto Ciccia et al.

MOLECULAR CELL (2010)

Article Biochemistry & Molecular Biology

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

Renee D. Paulsen et al.

MOLECULAR CELL (2009)

Article Biochemistry & Molecular Biology

Identification and characterization of FUS/TLS as a new target of ATM

Mary Gardiner et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

Jean-Philippe Gagne et al.

NUCLEIC ACIDS RESEARCH (2008)

Article Biochemistry & Molecular Biology

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

Anna E. O. Fisher et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Shuhei Matsuoka et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines

Atsushi Yoshimura et al.

CURRENT BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Rules for nuclear localization sequence recognition by karyopherinβ2

Brittany J. Lee et al.

Article Biochemistry & Molecular Biology

Domain Architectures and characterization of an RNA-binding protein, TLS

Y Iko et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Chemistry, Multidisciplinary

Chemistry and biology of DNA repair

OD Scharer

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)

Article Biochemistry & Molecular Biology

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

JM Pleschke et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Male sterility and enhanced radiation sensitivity in TLS-/- mice

M Kuroda et al.

EMBO JOURNAL (2000)

Article Biochemistry & Molecular Biology

Repair of endogenous DNA damage

T Lindahl et al.

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (2000)