期刊
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
卷 32, 期 5, 页码 952-962出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09603123.2020.1810209
关键词
Environmental factors; nasopharyngeal (NP) microbiota; bacterial diversity; 16s rRNA
资金
- National Natural Science Foundation of China [U1804184]
- Scientific and Technological Key Project of Henan Province [182102310178]
The nasopharynx is a key niche of the upper respiratory tract with a microbiota that when dysbiotic, is associated with respiratory diseases. Changes in environmental factors between spring and fall can influence the composition of the nasopharyngeal microbiota, significantly correlating to specific taxa.
The nasopharynx is a key niche of the upper respiratory tract which contains many commensal bacteria and potential pathogens. Dysbiosis of the nasopharyngeal (NP) microbiota is associated with a variety of respiratory diseases. Little is known about NP flora in healthy youth, nor about its relationship with environmental factors. We characterized NP microbiota using the 16S rRNA gene sequencing method, and compared microbial composition from subjects sampled in Spring and Fall when exposed to different environmental factors. Results showed that beta diversity was significantly different. PhylaAcidobacteria, Gemmatimonadetes, and genusSymbiobacteriumwere positively associated with PM2.5. GeneraStreptococcus, Prevotella, and[Prevotella]were positively correlated with temperature (T). Ozone (O-3) was associated with these floras for exposure that occurred 30 days prior to collection. These preliminary data suggest that the change in environmental factors between spring and fall can influence the composition of the NP microbiota, characterized by a significant correlation to specific taxa. These changes in NP microbiota might be a potential risk factor for respiratory disease.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据