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A genetic typing method for albino mutation in the Mongolian gerbil by PCR-RFLP analysis

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INTEGRATIVE ZOOLOGY
卷 16, 期 3, 页码 429-432

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WILEY
DOI: 10.1111/1749-4877.12483

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We established a PCR-RFLP analysis targeting the R77H mutation in the Tyrgene, as a more effective genotyping method to identify carriers (C/c) with the albino allele and agouti phenotypes. This breeding system targeting the R77H site serves as a useful cue for detecting C/c carriers with the agouti phenotype and facilitates obtaining albinos by mating agouti-phenotype carriers.
1. We established a PCR-RFLP analysis targeting R77H mutation in theTyrgene as a more effective genotyping to identify carrier (C/c) with the albino allele and the agouti phenotypes. 2. Our breeding system, which targets the R77H site, is a useful cue for detecting C/c carriers with the agouti-phenotype and helps us to obtain albinos by mating agouti-phenotype carriers.

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