期刊
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
卷 43, 期 1, 页码 345-353出版社
WILEY
DOI: 10.1002/hed.26486
关键词
COT; meta-analysis; minimally invasive surgery; TOETVA
资金
- Sichuan Science and Technology Program [2019YJ0038]
The TOETVA group had significantly longer operative time and larger amount of drainage compared to the COT group, but there were no significant differences in postoperative outcomes. Therefore, TOETVA appears to be a feasible and safe option for patients with benign thyroid nodules and selected differential thyroid carcinomas.
Background To conduct a meta-analysis to compare the safety and efficacy of transoral endoscopic thyroidectomy vestibular approach (TOETVA) with conventional open thyroidectomy (COT). Methods MEDLINE, EMBASE, Science Citation Index Expanded, and the Cochrane Central Register of Controlled Trials in the Cochrane Library from January 2007 to March 2020 were searched to identify studies comparing TOETVA and COT. Results Six eligible nonrandomized studies involving 1151 patients were included. Meta-analysis results revealed that TOETVA group had a significantly longer operative time (weighted mean difference [WMD], 66.09; 95% confidence interval [CI], 35.22-96.96;P < .0001) and larger amount of drainage (WMD, 98; 95% CI, 20.14-175.86;P= .01). There were no significant differences in terms of postoperative outcomes. Conclusion TOETVA appears to be as feasible and safe as the COT for the treatment of patients with benign thyroid nodules and selected differential thyroid carcinomas.
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